STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
scsCSimilar to Salmonella typhimurium suppressor for copper-sensitivity C precursor ScsC TR:O33919 (EMBL:U75949) fasta scores: E(): 0, 97.1% id in 207 aa. (207 aa)    
Predicted Functional Partners:
scsB
Similar to Salmonella typhimurium suppressor for copper-sensitivity B precursor ScsB TR:O33918 (EMBL:U75949) fasta scores: E(): 0, 95.4% id in 628 aa.
 
 
 0.996
scsD
Similar to Salmonella typhimurium suppressor for copper-sensitivity d scsd TR:O33920 (EMBL:U75949) fasta scores: E(): 0, 97.0% id in 168 aa, and to Haemophilus influenzae thioredoxin-like protein hi1115 hi1115 SW:THIX_HAEIN (P43787) fasta scores: E(): 3.2e-26, 40.6% id in 165 aa.
 
 
 0.990
dsbD
Thiol:disulfide interchange protein DsbD; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily.
  
 
 0.901
scsA
Similar to Salmonella typhimurium suppressor for copper-sensitivity a ScsA TR:O33917 (EMBL:U75949) fasta scores: E(): 0, 99.2% id in 120 aa.
     
 0.828
STY1153
Glucose-1-phosphatase precursor (G1Pase), secreted; Fasta hit to PPA_ECOLI (432 aa), 33% identity in 409 aa overlap; Orthologue of E. coli agp (AGP_ECOLI); Fasta hit to AGP_ECOLI (413 aa), 83% identity in 413 aa overlap.
     
 0.657
STY3639
Thioredoxin; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions; Belongs to the thioredoxin family.
      
 0.656
STY2842
Thioredoxin 2; Orthologue of E. coli yfiG (THI2_ECOLI); Fasta hit to THI2_ECOLI (139 aa), 94% identity in 139 aa overlap; Belongs to the thioredoxin family.
      
 0.614
STY1936
Disulfide bond formation protein B; Required for disulfide bond formation in some periplasmic proteins such as PhoA or OmpA. Acts by oxidizing the DsbA protein (By similarity); Belongs to the DsbB family.
  
 
 0.584
dsbG
Thiol:disulfide interchange protein DsbG precursor; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.
      
 0.541
STY1419
Similar to Escherichia coli probable pyruvate-flavodoxin oxidoreductase ydbK SW:NIFJ_ECOLI (P52647; P77238) (1174 aa) fasta scores: E(): 0, 92.9% id in 1174 aa; Orthologue of E. coli NIFJ_ECOLI; Fasta hit to NIFJ_ECOLI (1174 aa), 93% identity in 1174 aa overlap.
       0.527
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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