STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STY1170Putative oxidoreductase; Similar to Rhizobium meliloti myo-inositol 2-dehydrogenase idha SW:MI2D_RHIME (O68965) fasta scores: E(): 1.4e-14, 26.8% id in 370 aa; Orthologue of E. coli yjhC (YJHC_ECOLI); Fasta hit to YJHC_ECOLI (372 aa), 62% identity in 366 aa overlap. (367 aa)    
Predicted Functional Partners:
STY1169
Putative transporter; Similar to Acinetobacter calcoaceticus cis,cis-muconate transport protein muck SW:MUCK_ACICA (P94131) fasta scores: E(): 4.1e-26, 28.8% id in 382 aa; Orthologue of E. coli yjhB (YJHB_ECOLI); Fasta hit to YJHB_ECOLI (405 aa), 57% identity in 406 aa overlap.
  
  
 0.919
STY1167
Conserved hypothetical protein; Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta- anomer, accelerating the equilibrium between the alpha- and beta- anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses; Belongs to the NanM family.
 
   
 0.763
STY1166
Conserved hypothetical protein; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P).
 
  
 0.613
STY1164
Putative membrane transporter; Similar to Synechocystis sp sodium-coupled permease sll1087 TR:P74252 (EMBL:D90913) fasta scores: E(): 4.3e-17, 27.4% id in 266 aa; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
   
 0.605
STY1168
Putative secreted protein; Similar to Escherichia coli hypothetical 28.3 kda protein in feci-fimb intergenic region precursor yjha SW:YJHA_ECOLI (P39372) fasta scores: E(): 5.3e-10, 25.5% id in 243 aa.
     
 0.579
STY1165
Putative membrane transporter; Similar to Synechocystis sp sodium-coupled permease TR:Q55306 (EMBL:L77077) fasta scores: E(): 4.4e-19, 32.3% id in 167 aa; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
     
 0.546
STY2527
Putative lipopolysaccharide biosynthesis protein; Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily.
 
  
 0.546
STY4471
Sodium:solute symporter family protein; Transports acetate; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
      
 0.501
STY1180
Nucleation component of curlin monomers; Curlin is the structural subunit of the curli. Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin. The minor subunit is the nucleation component of curlin monomers; Belongs to the CsgA/CsgB family.
      
 0.497
STY3196
Lysyl tRNA synthetase (LysRS); Fasta hit to SYK2_ECOLI (504 aa), 90% identity in 504 aa overlap; Orthologue of E. coli lysS (SYK1_ECOLI); Fasta hit to SYK1_ECOLI (504 aa), 95% identity in 504 aa overlap; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
    0.496
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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