node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
STY0111 | STY0112 | gene:17584154 | gene:17584155 | Probable ATP-dependent helicase HepA; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. | DNA polymerase II; Orthologue of E. coli polB (DPO2_ECOLI); Fasta hit to DPO2_ECOLI (782 aa), 90% identity in 782 aa overlap. | 0.770 |
STY0111 | STY0430 | gene:17584154 | gene:17584456 | Probable ATP-dependent helicase HepA; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. | Exonuclease SbcD; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. | 0.467 |
STY0111 | STY1951 | gene:17584154 | gene:17585869 | Probable ATP-dependent helicase HepA; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. | Similar to Escherichia coli probable ATP-dependent helicase YoaA SW:YOAA_ECOLI (P76257) (636 aa) fasta scores: E(): 0, 95.1% id in 635 aa, and to Haemophilus influenzae probable ATP-dependent helicase Hi0387 SW:YOAA_HAEIN (P44680) (640 aa) fasta scores: E(): 0, 62.4% id in 633 aa, and to Streptomyces coelicolor putative ATP-dependent helicase SC4H2.23 TR:O69978 (EMBL:AL022268) (664 aa) fasta scores: E(): 2.1e-32, 33.6% id in 660 aa. | 0.804 |
STY0111 | STY2460 | gene:17584154 | gene:17586361 | Probable ATP-dependent helicase HepA; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. | Putative helicase; Orthologue of E. coli yejH (YEJH_ECOLI); Fasta hit to YEJH_ECOLI (586 aa), 95% identity in 586 aa overlap. | 0.892 |
STY0111 | STY3731 | gene:17584154 | gene:17587587 | Probable ATP-dependent helicase HepA; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. | DNA-directed RNA polymerase, beta'-subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.792 |
STY0111 | STY3732 | gene:17584154 | gene:17587588 | Probable ATP-dependent helicase HepA; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. | DNA-directed RNA polymerase, beta-subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.952 |
STY0111 | STY3881 | gene:17584154 | gene:17587738 | Probable ATP-dependent helicase HepA; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.883 |
STY0111 | STY3941 | gene:17584154 | gene:17587801 | Probable ATP-dependent helicase HepA; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. | DNA polymerase III beta-subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.844 |
STY0111 | rpoA | gene:17584154 | gene:17588211 | Probable ATP-dependent helicase HepA; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. | DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.950 |
STY0111 | rpoZ | gene:17584154 | gene:17587896 | Probable ATP-dependent helicase HepA; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. | DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity). | 0.952 |
STY0112 | STY0111 | gene:17584155 | gene:17584154 | DNA polymerase II; Orthologue of E. coli polB (DPO2_ECOLI); Fasta hit to DPO2_ECOLI (782 aa), 90% identity in 782 aa overlap. | Probable ATP-dependent helicase HepA; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. | 0.770 |
STY0112 | STY0430 | gene:17584155 | gene:17584456 | DNA polymerase II; Orthologue of E. coli polB (DPO2_ECOLI); Fasta hit to DPO2_ECOLI (782 aa), 90% identity in 782 aa overlap. | Exonuclease SbcD; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. | 0.469 |
STY0112 | STY1951 | gene:17584155 | gene:17585869 | DNA polymerase II; Orthologue of E. coli polB (DPO2_ECOLI); Fasta hit to DPO2_ECOLI (782 aa), 90% identity in 782 aa overlap. | Similar to Escherichia coli probable ATP-dependent helicase YoaA SW:YOAA_ECOLI (P76257) (636 aa) fasta scores: E(): 0, 95.1% id in 635 aa, and to Haemophilus influenzae probable ATP-dependent helicase Hi0387 SW:YOAA_HAEIN (P44680) (640 aa) fasta scores: E(): 0, 62.4% id in 633 aa, and to Streptomyces coelicolor putative ATP-dependent helicase SC4H2.23 TR:O69978 (EMBL:AL022268) (664 aa) fasta scores: E(): 2.1e-32, 33.6% id in 660 aa. | 0.788 |
STY0112 | STY2460 | gene:17584155 | gene:17586361 | DNA polymerase II; Orthologue of E. coli polB (DPO2_ECOLI); Fasta hit to DPO2_ECOLI (782 aa), 90% identity in 782 aa overlap. | Putative helicase; Orthologue of E. coli yejH (YEJH_ECOLI); Fasta hit to YEJH_ECOLI (586 aa), 95% identity in 586 aa overlap. | 0.438 |
STY0112 | STY3881 | gene:17584155 | gene:17587738 | DNA polymerase II; Orthologue of E. coli polB (DPO2_ECOLI); Fasta hit to DPO2_ECOLI (782 aa), 90% identity in 782 aa overlap. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.926 |
STY0112 | STY3941 | gene:17584155 | gene:17587801 | DNA polymerase II; Orthologue of E. coli polB (DPO2_ECOLI); Fasta hit to DPO2_ECOLI (782 aa), 90% identity in 782 aa overlap. | DNA polymerase III beta-subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.975 |
STY0430 | STY0111 | gene:17584456 | gene:17584154 | Exonuclease SbcD; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. | Probable ATP-dependent helicase HepA; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. | 0.467 |
STY0430 | STY0112 | gene:17584456 | gene:17584155 | Exonuclease SbcD; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. | DNA polymerase II; Orthologue of E. coli polB (DPO2_ECOLI); Fasta hit to DPO2_ECOLI (782 aa), 90% identity in 782 aa overlap. | 0.469 |
STY0430 | STY1951 | gene:17584456 | gene:17585869 | Exonuclease SbcD; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. | Similar to Escherichia coli probable ATP-dependent helicase YoaA SW:YOAA_ECOLI (P76257) (636 aa) fasta scores: E(): 0, 95.1% id in 635 aa, and to Haemophilus influenzae probable ATP-dependent helicase Hi0387 SW:YOAA_HAEIN (P44680) (640 aa) fasta scores: E(): 0, 62.4% id in 633 aa, and to Streptomyces coelicolor putative ATP-dependent helicase SC4H2.23 TR:O69978 (EMBL:AL022268) (664 aa) fasta scores: E(): 2.1e-32, 33.6% id in 660 aa. | 0.767 |
STY0430 | STY3732 | gene:17584456 | gene:17587588 | Exonuclease SbcD; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. | DNA-directed RNA polymerase, beta-subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.431 |