STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STY2373Putative sugar kinase; Shows weak similarity e.g. to Escherichia coli 1-phosphofructokinase SW:K1PF_ECOLI (P23539) (312 aa) fasta scores: E(): 4.3e-10, 25.7% id in 300 aa and Escherichia coli ribokinase rbsK SW:RBSK_ECOLI (P05054) (309 aa) fasta scores: E(): 1.9e-06, 22.3% id in 301 aa; Orthologue of E. coli YEGV_ECOLI; Fasta hit to YEGV_ECOLI (321 aa), 77% identity in 321 aa overlap. (321 aa)    
Predicted Functional Partners:
STY2372
Putative hydrolase; Shows weak similarity to Listeria monocytogenes ADP ribosyl glycohydrolase bvrC TR:Q9RLU1 (EMBL:AJ007877) (327 aa) fasta scores: E(): 3.3e-30, 33.5% id in 325 aa; Orthologue of E. coli YEGU_ECOLI; Fasta hit to YEGU_ECOLI (334 aa), 84% identity in 334 aa overlap.
   
 0.965
STY2371
Similar to Escherichia coli nucleoside permease NupG nupG SW:NUPG_ECOLI (P09452; P76653) (418 aa) fasta scores: E(): 0, 31.9% id in 417 aa and Escherichia coli xanthosine permease xapB SW:XAPB_ECOLI (P45562; P77729) (418 aa) fasta scores: E(): 0, 29.6% id in 419 aa. Contains hydrophobic, probable membrane-spanning regions; Fasta hit to NUPG_ECOLI (418 aa), 32% identity in 417 aa overlap; Orthologue of E. coli YEGT_ECOLI; Fasta hit to YEGT_ECOLI (425 aa), 95% identity in 425 aa overlap.
 
     0.889
STY3803
Hypothetical protein; Weakly similar to several including: Escherichia coli hypothetical 35.6 kDa protein YegU SW:YEGU_ECOLI (P76418) (334 aa) fasta scores: E(): 3e-12, 31.4% id in 344 aa, and to Listeria monocytogenes ADP ribosyl glycohydrolase BvrC TR:Q9RLU1 (EMBL:AJ007877) (327 aa) fasta scores: E(): 3.5e-10, 27.7% id in 343 aa.
 
   
 0.715
STY3897
High affinity ribose transport protein RbsD; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
 
  
 0.587
STY1419
Similar to Escherichia coli probable pyruvate-flavodoxin oxidoreductase ydbK SW:NIFJ_ECOLI (P52647; P77238) (1174 aa) fasta scores: E(): 0, 92.9% id in 1174 aa; Orthologue of E. coli NIFJ_ECOLI; Fasta hit to NIFJ_ECOLI (1174 aa), 93% identity in 1174 aa overlap.
     
 0.521
STY2374
Putative gntR-family transcriptional regulator; Orthologue of E. coli YEGW_ECOLI; Fasta hit to YEGW_ECOLI (248 aa), 92% identity in 248 aa overlap.
 
   
 0.514
STY3504
Conserved hypothetical protein; Orthologue of E. coli YRBL_ECOLI; Fasta hit to YRBL_ECOLI (210 aa), 77% identity in 210 aa overlap.
  
  
  0.512
STY2083
Conserved hypothetical protein; Orthologue of E. coli P76280; Fasta hit to P76280 (218 aa), 66% identity in 218 aa overlap.
  
   0.501
fbaB
Similar to Escherichia coli fructose-bisphosphate aldolase class I FbaB or DhnA SW:ALF1_ECOLI (P71295) (349 aa) fasta scores: E(): 0, 96.0% id in 349 aa; Orthologue of E. coli ALF1_ECOLI; Fasta hit to ALF1_ECOLI (349 aa), 96% identity in 349 aa overlap.
  
  
 0.482
STY0723
Pts system, N-acetylglucosamine-specific IIABC component; Orthologue of E. coli nagE (PTAA_ECOLI); Fasta hit to PTAA_ECOLI (648 aa), 93% identity in 648 aa overlap.
  
  
 0.471
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.