STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STY2710Transaldolase A; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (316 aa)    
Predicted Functional Partners:
STY2711
Transketolase 2; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 0.999
fbaB
Similar to Escherichia coli fructose-bisphosphate aldolase class I FbaB or DhnA SW:ALF1_ECOLI (P71295) (349 aa) fasta scores: E(): 0, 96.0% id in 349 aa; Orthologue of E. coli ALF1_ECOLI; Fasta hit to ALF1_ECOLI (349 aa), 96% identity in 349 aa overlap.
  
 
 0.992
STY3236
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 0.965
STY4417
Similar to Escherichia coli glucose-6-phosphate isomerase pgi SW:G6PI_ECOLI (P11537) (549 aa) fasta scores: E(): 0, 95.3% id in 548 aa, and to Haemophilus influenzae glucose-6-phosphate isomerase pgi SW:G6PI_HAEIN (P44312) (563 aa) fasta scores: E(): 0, 75.4% id in 549 aa; Belongs to the GPI family.
  
 
 0.950
STY1785
6-phosphofructokinase isozyme; Fasta hit to K1PF_ECOLI (312 aa), 31% identity in 311 aa overlap; Orthologue of E. coli pfkB (K6P2_ECOLI); Fasta hit to K6P2_ECOLI (309 aa), 93% identity in 308 aa overlap; Belongs to the carbohydrate kinase PfkB family.
   
 
 0.939
STY3436
Possible carbohydrate kinase; Similar to Bacillus subtilis 1-phosphofructokinase fruk or fruB SW:K1PF_BACSU (O31714) (303 aa) fasta scores: E(): 9.9e-28, 31.8% id in 305 aa; Belongs to the carbohydrate kinase PfkB family.
   
 
 0.939
STY1419
Similar to Escherichia coli probable pyruvate-flavodoxin oxidoreductase ydbK SW:NIFJ_ECOLI (P52647; P77238) (1174 aa) fasta scores: E(): 0, 92.9% id in 1174 aa; Orthologue of E. coli NIFJ_ECOLI; Fasta hit to NIFJ_ECOLI (1174 aa), 93% identity in 1174 aa overlap.
  
 
 0.932
STY3226
Fructose 1,6-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
  
 
 0.929
STY1793
Catalase HPII; Serves to protect cells from the toxic effects of hydrogen peroxide.
   
   0.927
STY2571
Similar to the N-terminal halves of transketolases e.g. Mus musculus transketolase tkt SW:TKT_MOUSE (P40142) (623 aa) fasta scores: E(): 5.6e-24, 33.0% id in 267 aa.
 
  
 0.926
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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