STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STY3335Probable AraC-family trancriptional regulatory protein; Similar to several proposed regulatory proteins e.g. Escherichia coli hypothetical transcriptional regulator in metc-sufi intergenic region yqhC SW:YQHC_ECOLI (Q46855) (318 aa) fasta scores: E(): 0, 84.2% id in 304 aa. (306 aa)    
Predicted Functional Partners:
STY3337
Similar to several alcohol dehydrogenases e.g. Clostridium acetobutylicum NADH-dependent butanol dehydrogenase a bdhA SW:ADHA_CLOAB (Q04944) (389 aa) fasta scores: E(): 0, 37.8% id in 365 aa. Also highly similar to Escherichia coli hypothetical oxidoreductase YqhD SW:YQHD_ECOLI (Q46856) (387 aa) fasta scores: E(): 0, 88.6% id in 387 aa; Orthologue of E. coli YQHD_ECOLI; Fasta hit to YQHD_ECOLI (387 aa), 89% identity in 387 aa overlap.
     
 0.666
yafB
Hypothetical oxidoreductase; Catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG).
 
   
 0.492
STY1253
Similar to Streptomyces coelicolor putative tetR-family protein SC7E4.35 TR:CAB94623 (EMBL:AL359214) (214 aa) fasta scores: E(): 2.5e-23, 35.5% id in 200 aa; Fasta hit to YJGJ_ECOLI (197 aa), 33% identity in 188 aa overlap; Orthologue of E. coli YCFQ_ECOLI; Fasta hit to YCFQ_ECOLI (210 aa), 80% identity in 210 aa overlap.
  
     0.472
STY0121
Arabinose operon regulatory protein; Orthologue of E. coli araC (ARAC_ECOLI); Fasta hit to ARAC_ECOLI (292 aa), 92% identity in 281 aa overlap.
  
   
 0.419
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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