STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STY4196Similar to Escherichia coli hypothetical transcriptional regulator in tref-kdgk intergenic region yhjC SW:YHJC_ECOLI (P37641) (299 aa) fasta scores: E(): 0, 66.6% id in 296 aa, and to Pseudomonas fluorescens transcriptional activator of pyoluteorin biosynthetic genes pltR TR:Q9X3Q9 (EMBL:AF081920) (343 aa) fasta scores: E(): 3.2e-21, 27.8% id in 291 aa; Fasta hit to YAFC_ECOLI (304 aa), 31% identity in 293 aa overlap; Fasta hit to YFER_ECOLI (308 aa), 30% identity in 260 aa overlap; Fasta hit to YEAT_ECOLI (307 aa), 31% identity in 293 aa overlap; Orthologue of E. coli yhjC (YHJC_ECOLI [...] (300 aa)    
Predicted Functional Partners:
STY2821
Similar to many transcriptional regulators e.g. Escherichia coli cyn operon transcriptional activator cynR SW:CYNR_ECOLI (P27111) (299 aa) fasta scores: E(): 5.4e-18, 30.1% id in 226 aa; Belongs to the LysR transcriptional regulatory family.
  
     0.722
STY2510
Similar to transcriptional regulators e.g. Bacillus subtilis hypothetical transcriptional regulator YvbU yvbU SW:YVBU_BACSU (O32255) (292 aa) fasta scores: E(): 8.9e-30, 34.2% id in 269 aa and Bacillus subtilis transcriptional regulatory protein GltC gltC SW:GLTC_BACSU (P20668) (300 aa) fasta scores: E(): 8.2e-19, 29.6% id in 274 aa.
  
     0.695
STY3944
Putative LysR-family transcriptioanl regulator; Weakly similar to many transcriptional regulators including: Escherichia coli hypothetical transcriptional regulator YfeR SW:YFER_ECOLI (P77500) (308 aa) fasta scores: E(): 9.6e-17, 26.4% id in 311 aa, and to Escherichia coli cyn operon transcriptional activator CynR SW:CYNR_ECOLI (P27111) (299 aa) fasta scores: E(): 2.1e-11, 26.3% id in 297 aa; Belongs to the LysR transcriptional regulatory family.
  
     0.695
STY1168
Putative secreted protein; Similar to Escherichia coli hypothetical 28.3 kda protein in feci-fimb intergenic region precursor yjha SW:YJHA_ECOLI (P39372) fasta scores: E(): 5.3e-10, 25.5% id in 243 aa.
      
 0.687
STY2410
Similar to transcriptional regulators e.g. Azospirillum brasilense galactose-binding protein regulator gbpR SW:GBPR_AZOBR (P52661) (342 aa) fasta scores: E(): 1.7e-27, 32.9% id in 289 aa and Agrobacterium tumefaciens pca operon transcriptional activator pcaQ SW:PCAQ_AGRTU (P52668) (311 aa) fasta scores: E(): 2.2e-21, 29.9% id in 294 aa; Belongs to the LysR transcriptional regulatory family.
  
     0.675
STY2655
Xanthosine operon transcriptional regulator; Fasta hit to YCJZ_ECOLI (299 aa), 31% identity in 264 aa overlap; Fasta hit to YNFL_ECOLI (297 aa), 36% identity in 284 aa overlap; Orthologue of E. coli xapR (XAPR_ECOLI); Fasta hit to XAPR_ECOLI (294 aa), 81% identity in 293 aa overlap; Belongs to the LysR transcriptional regulatory family.
  
     0.622
STY1537
Putative regulatory protein; Similar to Bacillus subtilis transcriptional regulatory protein GltR gltR SW:GLTR_BACSU (P94501; O07083) (296 aa) fasta scores: E(): 2.5e-32, 35.5% id in 282 aa; Orthologue of E. coli YNEJ_ECOLI; Fasta hit to YNEJ_ECOLI (293 aa), 85% identity in 283 aa overlap; Belongs to the LysR transcriptional regulatory family.
  
     0.616
STY1164
Putative membrane transporter; Similar to Synechocystis sp sodium-coupled permease sll1087 TR:P74252 (EMBL:D90913) fasta scores: E(): 4.3e-17, 27.4% id in 266 aa; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
      
 0.596
STY1165
Putative membrane transporter; Similar to Synechocystis sp sodium-coupled permease TR:Q55306 (EMBL:L77077) fasta scores: E(): 4.4e-19, 32.3% id in 167 aa; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
      
 0.596
STY3708
Possible LysR-family transcriptional regulatory protein; Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon.
  
     0.588
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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