STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STY4205Similar to Escherichia coli glutathione reductase gor SW:GSHR_ECOLI (P06715) (450 aa) fasta scores: E(): 0, 94.7% id in 450 aa, and to Haemophilus influenzae glutathione reductase HI0161 SW:GSHR_HAEIN (P43783) (456 aa) fasta scores: E(): 0, 74.8% id in 457 aa. (450 aa)    
Predicted Functional Partners:
btuE
Putative glutathione peroxidase/vitamin B12 transport periplasmic protein BtuE; Non-specific peroxidase that can use thioredoxin or glutathione as a reducing agent.
  
 0.965
STY3248
Glutathione synthetase; Orthologue of E. coli gshB (GSHB_ECOLI); Fasta hit to GSHB_ECOLI (316 aa), 90% identity in 315 aa overlap.
     
 0.928
ggt
Similar to Escherichia coli gamma-glutamyltranspeptidase precursor ggt SW:GGT_ECOLI (P18956) (580 aa) fasta scores: E(): 0, 91.4% id in 580 aa, and to Helicobacter pylori J99 gamma-glutamyltranspeptidase ggt TR:Q9ZK95 (EMBL:AE001532) (567 aa) fasta scores: E(): 0, 52.7% id in 537 aa. Contains N-terminal signal sequence, probable secreted protein.
     
 0.924
STY1671
Glutathione S-transferase; Orthologue of E. coli gst (GT_ECOLI); Fasta hit to GT_ECOLI (201 aa), 83% identity in 200 aa overlap; Belongs to the GST superfamily.
   
 0.916
STY2578
Similar to glutathione-S transferase-family proteins e.g. Dianthus caryophyllus glutathione S-transferase 1 gst1 or carsr8 SW:GTT1_DIACA (P28342) (221 aa) fasta scores: E(): 4e-07, 34.7% id in 196 aa; Orthologue of E. coli YFCF_ECOLI; Fasta hit to YFCF_ECOLI (214 aa), 81% identity in 214 aa overlap.
    
 0.913
yliJ
Glutathione s-transferase family protein; Similar to Escherichia coli hypothetical 23.9 kDa protein in moea-dacc intergenic region yliJ SW:YLIJ_ECOLI (P75805) (210 aa) fasta scores: E(): 0, 83.2% id in 208 aa, and to Hyoscyamus muticus glutathione s-transferase SW:GTH_HYOMU (P46423) (212 aa) fasta scores: E(): 7.5e-13, 27.4% id in 208 aa; Orthologue of E. coli YLIJ_ECOLI; Fasta hit to YLIJ_ECOLI (210 aa), 83% identity in 208 aa overlap.
   
 0.912
STY4465
Putative glutathione S transferase; Similar to Pseudomonas syringae GstA TR:AAF71510 (EMBL:AF232006) (208 aa) fasta scores: E(): 3.3e-22, 45.0% id in 222 aa, and to Schizosaccharomyces pombe putative glutathione S transferase SPAC688.04C TR:CAB90771 (EMBL:AL355632) (242 aa) fasta scores: E(): 3.2e-24, 39.5% id in 210 aa; Belongs to the GST superfamily.
    
 0.911
STY3310
Glutathionylspermidine synthetase/amidase; Orthologue of E. coli gsp (GSP_ECOLI); Fasta hit to GSP_ECOLI (619 aa), 90% identity in 618 aa overlap.
     
 0.906
ybbN
Thioredoxin-like protein; Similar to Escherichia coli hypothetical 33.1 kDa protein in usha-tesa intergenic region ybbN SW:YBBN_ECOLI (P77395) (296 aa) fasta scores: E(): 0, 93.8% id in 290 aa, and to Alicyclobacillus acidocaldarius thioredoxin trxA SW:THIO_ALIAC (P80579) (105 aa) fasta scores: E(): 1.5e-07, 35.6% id in 104 aa, and to Escherichia coli thioredoxin 2 trxC SW:THI2_ECOLI (P33636; P76593; P77000; P77001) (139 aa) fasta scores: E(): 1e-06, 29.5% id in 105 aa. Note that the redox-active disulphide pair is not conserved; Orthologue of E. coli YBBN_ECOLI; Fasta hit to YBBN_ECOL [...]
  
 
 0.879
STY0780
Dihydrolipoamide succinyltransferase component (E2); E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 0.862
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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