STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pilNSimilar to the N-terminus Escherichia coli lipoprotein pilN TR:O07372 (EMBL:D88588) (560 aa) fasta scores: E(): 4.6e-17, 44.9% id in 136 aa. The C-terminus is encoded by STY4541 on the opposite strand. This section of the gene appears to have been inverted around a 10bp inverted repeat. (142 aa)    
Predicted Functional Partners:
pilM
Putative exported protein; Previously sequenced Salmonella typhi PilM TR:Q9RHF3 (EMBL:AF000001) (139 aa) fasta scores: E(): 0, 100.0% id in 139 aa. Also similar to Escherichia coli plasmid IncI1 R64 protein PilM TR:O07371 (EMBL:D88588) (145 aa) fasta scores: E(): 1.2e-24, 49.6% id in 129 aa. Contains a possible N-terminal signal sequence.
      
 0.711
pilQ
Nucleotide-binding protein; Previously sequenced Salmonella typhi PilQ TR:Q9LBE1 (EMBL:AF000001) (571 aa) fasta scores: E(): 0, 100.0% id in 571aa. Also similar to Escherichia coli plasmid IncI1 R64 nucleotide-binding protein PilQ TR:O07375 (EMBL:D88588) (517 aa) fasta scores: E(): 0, 51.3% id in 519 aa.
      
 0.649
pilS
Prepilin; Previously sequenced Salmonella typhi PilS protein TR:Q9ZIU9 (EMBL:AF000001) (206 aa) fasta scores: E(): 0, 100.0% id in 206 aa. Also similar to Escherichia coli plasmid IncI1 R64 type IV prepilin pilS TR:O88170 (EMBL:AB007463) (204 aa) fasta scores: E(): 1.6e-31, 49.2% id in 193 aa.
      
 0.649
pilK
Putative exported protein; Weakly similar to Escherichia coli plasmid IncI1 R64 PilK protein TR:O07369 (EMBL:D88588) (196 aa) fasta scores: E(): 1.8, 25.3% id in 158 aa. Contains a possible N-terminal signal sequence.
      
 0.600
pilV
Prepilin; Previously sequenced Salmonella typhi PilV TR:O51801 (EMBL:AF000001) (435 aa) fasta scores: E(): 0, 100.0% id in 435 aa. Also similar to Escherichia coli shufflon protein A' SW:SHU2_ECOLI (P09746) (430 aa) fasta scores: E(): 0, 49.5% id in 434 aa. Contains multiple possible membrane spanning hydrophobic domains.
      
 0.561
STY1904
Outer membrane lipoprotein; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
      
 0.518
pilP
Pilus assembly protein; Previously sequenced Salmonella typhi PilP TR:Q9RHF2 (EMBL:AF000001) (156 aa) fasta scores: E(): 0, 100.0% id in 156 aa. Also similar to Escherichia coli plasmid IncI1 R64 PilP protein TR:O07374 (EMBL:D88588) (150 aa) fasta scores: E(): 5.8e-10, 43.2% id in 132 aa.
      
 0.513
rfbN
Putative rhamnosyltransferase; Similar to many glycosyltransferases e.g. Salmonella typhimurium group B putative rhamnosyltransferase RfbN rfbN SW:RFBN_SALTY (P26403) (314 aa) fasta scores: E(): 0, 99.0% id in 314 aa and Salmonella typhimurium group E1 rhamnosyl transferase rfbN TR:Q54129 (EMBL:X60665) (315 aa) fasta scores: E(): 0, 74.4% id in 312 aa.
      
 0.501
pilR
Putative membrane protein; Previously sequenced Salmonella typhi PilR TR:Q9ZIV0 (EMBL:AF000001) (361 aa) fasta scores: E(): 0, 100.0% id in 361 aa. Also similar to Escherichia coli plasmid IncI1 R64 integral membrane protein pilR TR:O07376 (EMBL:D88588) (365 aa) fasta scores: E(): 0, 44.5% id in 357 aa. Contains possible membrane spanning hydrophobic domains.
      
 0.501
pilU
Prepilin peptidase; Previously sequenced Salmonella typhi PilU protein TR:Q9ZIU7 (EMBL:AF000001) (220 aa) fasta scores: E(): 0, 100.0% id in 220 aa. Also similar to Escherichia coli plasmid IncI1 R64 prepilin peptidase pilU TR:O07379 (EMBL:D88588) (218 aa) fasta scores: E(): 2e-25, 34.4% id in 221 aa. Contains multiple possible membrane spanning hydrophobic domains.
      
 0.487
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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