STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sucA2-oxoglutarate dehydrogenase, E1 component; Identified by similarity to SP:P20707; match to protein family HMM PF00676; match to protein family HMM PF02779; match to protein family HMM TIGR00239. (943 aa)    
Predicted Functional Partners:
sucB
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 0.999
lpdA_1
Dihydrolipoyl dehydrogenase; Identified by similarity to SP:P31052; match to protein family HMM PF00070; match to protein family HMM PF00890; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01350.
 
 0.990
sucC
succinate-CoA ligase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 
 0.987
lpdA_2
Dihydrolipoyl dehydrogenase; Identified by similarity to SP:P14218; match to protein family HMM PF00070; match to protein family HMM PF00890; match to protein family HMM PF02852; match to protein family HMM PF03486; match to protein family HMM PF07992; match to protein family HMM TIGR01350.
 
 0.984
icd_1
Isocitrate dehydrogenase, NADP-dependent; Identified by match to protein family HMM PF00180; match to protein family HMM TIGR00183.
   
 
 0.979
aceF
Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 0.978
bkdC
2-oxoisovalerate dehydrogenase E3 component, dihydrolipoyl dehydrogenase; Identified by similarity to SP:P09063; match to protein family HMM PF00070; match to protein family HMM PF01134; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01350.
  
 0.976
nuoD
NADH-quinone oxidoreductase, C/D subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
   
 
 0.976
bkdB
2-oxoisovalerate dehydrogenase E2 component, dihydrolipoamide acyltransferase; Identified by similarity to SP:P09062; match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817.
 0.967
acoC
Acetoin dehydrogenase E2 component, dihydrolipoamide acetyltransferase; Identified by similarity to SP:Q59695; match to protein family HMM PF00364; match to protein family HMM PF00561; match to protein family HMM PF00975.
  
 0.945
Your Current Organism:
Pseudomonas protegens
NCBI taxonomy Id: 220664
Other names: P. protegens Pf-5, Pseudomonas fluorescens Pf-5, Pseudomonas protegens Pf-5, Pseudomonas protegens str. Pf-5, Pseudomonas protegens strain Pf-5, Pseudomonas sp. Pf-5
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.