node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
aceF | acoC | PFL_0508 | PFL_2172 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Acetoin dehydrogenase E2 component, dihydrolipoamide acetyltransferase; Identified by similarity to SP:Q59695; match to protein family HMM PF00364; match to protein family HMM PF00561; match to protein family HMM PF00975. | 0.907 |
aceF | nuoD | PFL_0508 | PFL_3899 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | NADH-quinone oxidoreductase, C/D subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family. | 0.730 |
aceF | sdhA | PFL_0508 | PFL_1716 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Succinate dehydrogenase, flavoprotein subunit; Identified by similarity to SP:P10444; match to protein family HMM PF00890; match to protein family HMM PF01266; match to protein family HMM PF02910; match to protein family HMM TIGR01812; match to protein family HMM TIGR01816; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.578 |
aceF | sdhB | PFL_0508 | PFL_1717 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Succinate dehydrogenase, iron-sulfur protein; Identified by similarity to SP:P07014; match to protein family HMM TIGR00384. | 0.648 |
aceF | sdhC | PFL_0508 | PFL_1714 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Succinate dehydrogenase, cytochrome b556 subunit; Identified by similarity to SP:P10446; match to protein family HMM PF01127; match to protein family HMM TIGR02970. | 0.480 |
aceF | sdhD | PFL_0508 | PFL_1715 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Succinate dehydrogenase, hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH). | 0.443 |
aceF | sucA | PFL_0508 | PFL_1718 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 2-oxoglutarate dehydrogenase, E1 component; Identified by similarity to SP:P20707; match to protein family HMM PF00676; match to protein family HMM PF02779; match to protein family HMM TIGR00239. | 0.978 |
aceF | sucC | PFL_0508 | PFL_1721 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | succinate-CoA ligase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.947 |
aceF | sucD | PFL_0508 | PFL_1722 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | succinate-CoA ligase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.941 |
acoC | aceF | PFL_2172 | PFL_0508 | Acetoin dehydrogenase E2 component, dihydrolipoamide acetyltransferase; Identified by similarity to SP:Q59695; match to protein family HMM PF00364; match to protein family HMM PF00561; match to protein family HMM PF00975. | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.907 |
acoC | nuoD | PFL_2172 | PFL_3899 | Acetoin dehydrogenase E2 component, dihydrolipoamide acetyltransferase; Identified by similarity to SP:Q59695; match to protein family HMM PF00364; match to protein family HMM PF00561; match to protein family HMM PF00975. | NADH-quinone oxidoreductase, C/D subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family. | 0.800 |
acoC | sdhA | PFL_2172 | PFL_1716 | Acetoin dehydrogenase E2 component, dihydrolipoamide acetyltransferase; Identified by similarity to SP:Q59695; match to protein family HMM PF00364; match to protein family HMM PF00561; match to protein family HMM PF00975. | Succinate dehydrogenase, flavoprotein subunit; Identified by similarity to SP:P10444; match to protein family HMM PF00890; match to protein family HMM PF01266; match to protein family HMM PF02910; match to protein family HMM TIGR01812; match to protein family HMM TIGR01816; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.627 |
acoC | sdhB | PFL_2172 | PFL_1717 | Acetoin dehydrogenase E2 component, dihydrolipoamide acetyltransferase; Identified by similarity to SP:Q59695; match to protein family HMM PF00364; match to protein family HMM PF00561; match to protein family HMM PF00975. | Succinate dehydrogenase, iron-sulfur protein; Identified by similarity to SP:P07014; match to protein family HMM TIGR00384. | 0.722 |
acoC | sdhC | PFL_2172 | PFL_1714 | Acetoin dehydrogenase E2 component, dihydrolipoamide acetyltransferase; Identified by similarity to SP:Q59695; match to protein family HMM PF00364; match to protein family HMM PF00561; match to protein family HMM PF00975. | Succinate dehydrogenase, cytochrome b556 subunit; Identified by similarity to SP:P10446; match to protein family HMM PF01127; match to protein family HMM TIGR02970. | 0.492 |
acoC | sdhD | PFL_2172 | PFL_1715 | Acetoin dehydrogenase E2 component, dihydrolipoamide acetyltransferase; Identified by similarity to SP:Q59695; match to protein family HMM PF00364; match to protein family HMM PF00561; match to protein family HMM PF00975. | Succinate dehydrogenase, hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH). | 0.401 |
acoC | sucA | PFL_2172 | PFL_1718 | Acetoin dehydrogenase E2 component, dihydrolipoamide acetyltransferase; Identified by similarity to SP:Q59695; match to protein family HMM PF00364; match to protein family HMM PF00561; match to protein family HMM PF00975. | 2-oxoglutarate dehydrogenase, E1 component; Identified by similarity to SP:P20707; match to protein family HMM PF00676; match to protein family HMM PF02779; match to protein family HMM TIGR00239. | 0.945 |
acoC | sucC | PFL_2172 | PFL_1721 | Acetoin dehydrogenase E2 component, dihydrolipoamide acetyltransferase; Identified by similarity to SP:Q59695; match to protein family HMM PF00364; match to protein family HMM PF00561; match to protein family HMM PF00975. | succinate-CoA ligase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.953 |
acoC | sucD | PFL_2172 | PFL_1722 | Acetoin dehydrogenase E2 component, dihydrolipoamide acetyltransferase; Identified by similarity to SP:Q59695; match to protein family HMM PF00364; match to protein family HMM PF00561; match to protein family HMM PF00975. | succinate-CoA ligase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.944 |
nuoD | aceF | PFL_3899 | PFL_0508 | NADH-quinone oxidoreductase, C/D subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family. | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.730 |
nuoD | acoC | PFL_3899 | PFL_2172 | NADH-quinone oxidoreductase, C/D subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family. | Acetoin dehydrogenase E2 component, dihydrolipoamide acetyltransferase; Identified by similarity to SP:Q59695; match to protein family HMM PF00364; match to protein family HMM PF00561; match to protein family HMM PF00975. | 0.800 |