STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hcnBHydrogen cyanide synthase HcnB; Previously identified and sequenced. See Laville et al 1998 (PMID: 9620970) for more information; identified by similarity to GB:AAF21029.2; match to protein family HMM PF00070; match to protein family HMM PF04324; match to protein family HMM PF07992. (469 aa)    
Predicted Functional Partners:
hcnC
Hydrogen cyanide synthase HcnC; Previously identified and sequenced. See Laville et al 1998 (PMID: 9620970) for more information; identified by similarity to GB:AAC38596.1; match to protein family HMM PF01266.
 
 0.998
hcnA
Hydrogen cyanide synthase HcnA; Previously identified and sequenced. See Laville et al 1998 (PMID: 9620970) for more information; identified by similarity to GB:AAF21028.1; match to protein family HMM PF00111.
 
  
 0.996
glyA_1
Glycine hydroxymethyltransferase; Identified by similarity to SP:P00477; match to protein family HMM PF00464.
  
 
 0.909
glyA_2
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.909
glyA_3
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.909
PFL_1411
FAD dependent oxidoreductase; Identified by match to protein family HMM PF01266.
 
 
 0.823
pepA
Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
     
  0.800
pepN
Membrane alanyl aminopeptidase; Identified by match to protein family HMM PF01433; match to protein family HMM TIGR02414.
     
  0.800
gshB
Glutathione synthase; Identified by similarity to SP:P04425; match to protein family HMM PF02951; match to protein family HMM PF02955; match to protein family HMM PF08443; match to protein family HMM TIGR01380; Belongs to the prokaryotic GSH synthase family.
     
  0.800
thiO
Glycine oxidase ThiO; Identified by match to protein family HMM PF01266; match to protein family HMM TIGR02352.
 
 
 0.640
Your Current Organism:
Pseudomonas protegens
NCBI taxonomy Id: 220664
Other names: P. protegens Pf-5, Pseudomonas fluorescens Pf-5, Pseudomonas protegens Pf-5, Pseudomonas protegens str. Pf-5, Pseudomonas protegens strain Pf-5, Pseudomonas sp. Pf-5
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