node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PFL_6057 | PFL_6269 | PFL_6057 | PFL_6269 | Putative exodeoxyribonuclease III; Identified by match to protein family HMM PF03372; match to protein family HMM TIGR00633. | Hypothetical protein. | 0.796 |
PFL_6057 | alkA | PFL_6057 | PFL_4632 | Putative exodeoxyribonuclease III; Identified by match to protein family HMM PF03372; match to protein family HMM TIGR00633. | DNA-3-methyladenine glycosylase II; Identified by similarity to SP:P04395; match to protein family HMM PF00730; match to protein family HMM PF06029. | 0.774 |
PFL_6057 | birA | PFL_6057 | PFL_5601 | Putative exodeoxyribonuclease III; Identified by match to protein family HMM PF03372; match to protein family HMM TIGR00633. | Bifunctional protein BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.800 |
PFL_6057 | dnaN | PFL_6057 | PFL_0002 | Putative exodeoxyribonuclease III; Identified by match to protein family HMM PF03372; match to protein family HMM TIGR00633. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.781 |
PFL_6057 | hfq | PFL_6057 | PFL_0566 | Putative exodeoxyribonuclease III; Identified by match to protein family HMM PF03372; match to protein family HMM TIGR00633. | RNA chaperone Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.734 |
PFL_6057 | mutY | PFL_6057 | PFL_0358 | Putative exodeoxyribonuclease III; Identified by match to protein family HMM PF03372; match to protein family HMM TIGR00633. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.730 |
PFL_6057 | nth | PFL_6057 | PFL_4850 | Putative exodeoxyribonuclease III; Identified by match to protein family HMM PF03372; match to protein family HMM TIGR00633. | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.916 |
PFL_6057 | polA | PFL_6057 | PFL_0082 | Putative exodeoxyribonuclease III; Identified by match to protein family HMM PF03372; match to protein family HMM TIGR00633. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.839 |
PFL_6057 | ung | PFL_6057 | PFL_1435 | Putative exodeoxyribonuclease III; Identified by match to protein family HMM PF03372; match to protein family HMM TIGR00633. | uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. | 0.699 |
PFL_6057 | xth | PFL_6057 | PFL_3928 | Putative exodeoxyribonuclease III; Identified by match to protein family HMM PF03372; match to protein family HMM TIGR00633. | Exodeoxyribonuclease III; Identified by match to protein family HMM PF03372; match to protein family HMM TIGR00195; match to protein family HMM TIGR00633. | 0.919 |
PFL_6269 | PFL_6057 | PFL_6269 | PFL_6057 | Hypothetical protein. | Putative exodeoxyribonuclease III; Identified by match to protein family HMM PF03372; match to protein family HMM TIGR00633. | 0.796 |
PFL_6269 | alkA | PFL_6269 | PFL_4632 | Hypothetical protein. | DNA-3-methyladenine glycosylase II; Identified by similarity to SP:P04395; match to protein family HMM PF00730; match to protein family HMM PF06029. | 0.547 |
PFL_6269 | dnaN | PFL_6269 | PFL_0002 | Hypothetical protein. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.975 |
PFL_6269 | mutY | PFL_6269 | PFL_0358 | Hypothetical protein. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.416 |
PFL_6269 | nth | PFL_6269 | PFL_4850 | Hypothetical protein. | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.526 |
PFL_6269 | polA | PFL_6269 | PFL_0082 | Hypothetical protein. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.943 |
PFL_6269 | xth | PFL_6269 | PFL_3928 | Hypothetical protein. | Exodeoxyribonuclease III; Identified by match to protein family HMM PF03372; match to protein family HMM TIGR00195; match to protein family HMM TIGR00633. | 0.796 |
alkA | PFL_6057 | PFL_4632 | PFL_6057 | DNA-3-methyladenine glycosylase II; Identified by similarity to SP:P04395; match to protein family HMM PF00730; match to protein family HMM PF06029. | Putative exodeoxyribonuclease III; Identified by match to protein family HMM PF03372; match to protein family HMM TIGR00633. | 0.774 |
alkA | PFL_6269 | PFL_4632 | PFL_6269 | DNA-3-methyladenine glycosylase II; Identified by similarity to SP:P04395; match to protein family HMM PF00730; match to protein family HMM PF06029. | Hypothetical protein. | 0.547 |
alkA | mutY | PFL_4632 | PFL_0358 | DNA-3-methyladenine glycosylase II; Identified by similarity to SP:P04395; match to protein family HMM PF00730; match to protein family HMM PF06029. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.435 |