node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
bluB | cobB | PFL_4429 | PFL_4430 | cob(II)yrinic acid a,c-diamide reductase; Identified by match to protein family HMM PF00881; match to protein family HMM TIGR02476. | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.985 |
bluB | cobC-2 | PFL_4429 | PFL_4427 | cob(II)yrinic acid a,c-diamide reductase; Identified by match to protein family HMM PF00881; match to protein family HMM TIGR02476. | Threonine-phosphate decarboxylase; Identified by match to protein family HMM PF00155; match to protein family HMM TIGR01140. | 0.937 |
bluB | cobD | PFL_4429 | PFL_4428 | cob(II)yrinic acid a,c-diamide reductase; Identified by match to protein family HMM PF00881; match to protein family HMM TIGR02476. | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.928 |
bluB | cobH | PFL_4429 | PFL_0658 | cob(II)yrinic acid a,c-diamide reductase; Identified by match to protein family HMM PF00881; match to protein family HMM TIGR02476. | precorrin-8X methylmutase; Identified by similarity to SP:P21638; match to protein family HMM PF02570. | 0.578 |
bluB | cobJ | PFL_4429 | PFL_0660 | cob(II)yrinic acid a,c-diamide reductase; Identified by match to protein family HMM PF00881; match to protein family HMM TIGR02476. | CbiG protein/precorrin-3B C17-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM PF01890; match to protein family HMM TIGR01466. | 0.638 |
bluB | cobN | PFL_4429 | PFL_3654 | cob(II)yrinic acid a,c-diamide reductase; Identified by match to protein family HMM PF00881; match to protein family HMM TIGR02476. | Cobaltochelatase, CobN subunit; Identified by match to protein family HMM PF02514; match to protein family HMM TIGR02257. | 0.637 |
bluB | cobO | PFL_4429 | PFL_4431 | cob(II)yrinic acid a,c-diamide reductase; Identified by match to protein family HMM PF00881; match to protein family HMM TIGR02476. | cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.949 |
bluB | cobQ | PFL_4429 | PFL_4426 | cob(II)yrinic acid a,c-diamide reductase; Identified by match to protein family HMM PF00881; match to protein family HMM TIGR02476. | Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.915 |
bluB | cobT | PFL_4429 | PFL_4424 | cob(II)yrinic acid a,c-diamide reductase; Identified by match to protein family HMM PF00881; match to protein family HMM TIGR02476. | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.996 |
bluB | cobU | PFL_4429 | PFL_4425 | cob(II)yrinic acid a,c-diamide reductase; Identified by match to protein family HMM PF00881; match to protein family HMM TIGR02476. | Adenosylcobinamide kinase/adenosylcobinamidephosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.950 |
cobB | bluB | PFL_4430 | PFL_4429 | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | cob(II)yrinic acid a,c-diamide reductase; Identified by match to protein family HMM PF00881; match to protein family HMM TIGR02476. | 0.985 |
cobB | cobC-2 | PFL_4430 | PFL_4427 | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Threonine-phosphate decarboxylase; Identified by match to protein family HMM PF00155; match to protein family HMM TIGR01140. | 0.956 |
cobB | cobD | PFL_4430 | PFL_4428 | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.979 |
cobB | cobH | PFL_4430 | PFL_0658 | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | precorrin-8X methylmutase; Identified by similarity to SP:P21638; match to protein family HMM PF02570. | 0.994 |
cobB | cobJ | PFL_4430 | PFL_0660 | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CbiG protein/precorrin-3B C17-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM PF01890; match to protein family HMM TIGR01466. | 0.956 |
cobB | cobN | PFL_4430 | PFL_3654 | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Cobaltochelatase, CobN subunit; Identified by match to protein family HMM PF02514; match to protein family HMM TIGR02257. | 0.983 |
cobB | cobO | PFL_4430 | PFL_4431 | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.994 |
cobB | cobQ | PFL_4430 | PFL_4426 | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.990 |
cobB | cobT | PFL_4430 | PFL_4424 | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.982 |
cobB | cobU | PFL_4430 | PFL_4425 | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Adenosylcobinamide kinase/adenosylcobinamidephosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.978 |