node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
dnaC | lp_0012 | lp_0014 | lp_0012 | Replicative DNA helicase DnaC; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | Phosphoesterase, DHH family; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. | 0.852 |
dnaC | lp_0015 | lp_0014 | lp_0015 | Replicative DNA helicase DnaC; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | Transport protein, major facilitator superfamily (MFS). | 0.449 |
dnaC | proB | lp_0014 | lp_0016 | Replicative DNA helicase DnaC; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.440 |
dnaC | rplI | lp_0014 | lp_0013 | Replicative DNA helicase DnaC; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 50S ribosomal protein L9; Binds to the 23S rRNA. | 0.891 |
lp_0012 | dnaC | lp_0012 | lp_0014 | Phosphoesterase, DHH family; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. | Replicative DNA helicase DnaC; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.852 |
lp_0012 | lp_0015 | lp_0012 | lp_0015 | Phosphoesterase, DHH family; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. | Transport protein, major facilitator superfamily (MFS). | 0.410 |
lp_0012 | proB | lp_0012 | lp_0016 | Phosphoesterase, DHH family; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.420 |
lp_0012 | rplI | lp_0012 | lp_0013 | Phosphoesterase, DHH family; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. | 50S ribosomal protein L9; Binds to the 23S rRNA. | 0.982 |
lp_0015 | dnaC | lp_0015 | lp_0014 | Transport protein, major facilitator superfamily (MFS). | Replicative DNA helicase DnaC; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.449 |
lp_0015 | lp_0012 | lp_0015 | lp_0012 | Transport protein, major facilitator superfamily (MFS). | Phosphoesterase, DHH family; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. | 0.410 |
lp_0015 | proA | lp_0015 | lp_0017 | Transport protein, major facilitator superfamily (MFS). | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.659 |
lp_0015 | proB | lp_0015 | lp_0016 | Transport protein, major facilitator superfamily (MFS). | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.741 |
lp_0015 | rplI | lp_0015 | lp_0013 | Transport protein, major facilitator superfamily (MFS). | 50S ribosomal protein L9; Binds to the 23S rRNA. | 0.416 |
proA | lp_0015 | lp_0017 | lp_0015 | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | Transport protein, major facilitator superfamily (MFS). | 0.659 |
proA | proB | lp_0017 | lp_0016 | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.999 |
proA | rplI | lp_0017 | lp_0013 | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 50S ribosomal protein L9; Binds to the 23S rRNA. | 0.411 |
proB | dnaC | lp_0016 | lp_0014 | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | Replicative DNA helicase DnaC; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.440 |
proB | lp_0012 | lp_0016 | lp_0012 | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | Phosphoesterase, DHH family; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. | 0.420 |
proB | lp_0015 | lp_0016 | lp_0015 | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | Transport protein, major facilitator superfamily (MFS). | 0.741 |
proB | proA | lp_0016 | lp_0017 | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.999 |