| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| dhaP | glpD | lp_0171 | lp_0371 | Dihydroxyacetone transport protein; Transporter that facilitates the transmembrane diffusion of water, dihydroxyacetone, glycerol and H(2)O(2). Is not permeable to urea and D/L-lactic acid; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Glycerol-3-phosphate dehydrogenase,FAD-dependent. | 0.818 |
| dhaP | glpK | lp_0171 | lp_0370 | Dihydroxyacetone transport protein; Transporter that facilitates the transmembrane diffusion of water, dihydroxyacetone, glycerol and H(2)O(2). Is not permeable to urea and D/L-lactic acid; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.818 |
| dhaP | gykA | lp_0171 | lp_0834 | Dihydroxyacetone transport protein; Transporter that facilitates the transmembrane diffusion of water, dihydroxyacetone, glycerol and H(2)O(2). Is not permeable to urea and D/L-lactic acid; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. | 0.594 |
| glpD | dhaP | lp_0371 | lp_0171 | Glycerol-3-phosphate dehydrogenase,FAD-dependent. | Dihydroxyacetone transport protein; Transporter that facilitates the transmembrane diffusion of water, dihydroxyacetone, glycerol and H(2)O(2). Is not permeable to urea and D/L-lactic acid; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.818 |
| glpD | glpF1 | lp_0371 | lp_0108 | Glycerol-3-phosphate dehydrogenase,FAD-dependent. | Glycerol uptake facilitator protein; Transporter that facilitates the transmembrane diffusion of D/L-lactic acid. Is involved in the cellular racemization of lactate and lactate metabolism. The transported molecule is indeed lactic acid and not the lactate anion, in agreement with the assumption that, with very few exceptions, MIPs (major intrinsic proteins) only facilitate the transport of uncharged solutes. Also facilitates urea and H(2)O(2) diffusion across membranes, but is not permeable to water, glycerol and dihydroxyacetone; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.604 |
| glpD | glpF3 | lp_0371 | lp_0372 | Glycerol-3-phosphate dehydrogenase,FAD-dependent. | Glycerol uptake facilitator protein; Transporter that facilitates the transmembrane diffusion of water, dihydroxyacetone, glycerol and H(2)O(2). Is not permeable to urea and D/L-lactic acid; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.984 |
| glpD | glpK | lp_0371 | lp_0370 | Glycerol-3-phosphate dehydrogenase,FAD-dependent. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.998 |
| glpD | gykA | lp_0371 | lp_0834 | Glycerol-3-phosphate dehydrogenase,FAD-dependent. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. | 0.980 |
| glpD | plsY | lp_0371 | lp_1842 | Glycerol-3-phosphate dehydrogenase,FAD-dependent. | Acyl-phosphate glycerol 3-phosphate acyltransferase; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. | 0.918 |
| glpF1 | glpD | lp_0108 | lp_0371 | Glycerol uptake facilitator protein; Transporter that facilitates the transmembrane diffusion of D/L-lactic acid. Is involved in the cellular racemization of lactate and lactate metabolism. The transported molecule is indeed lactic acid and not the lactate anion, in agreement with the assumption that, with very few exceptions, MIPs (major intrinsic proteins) only facilitate the transport of uncharged solutes. Also facilitates urea and H(2)O(2) diffusion across membranes, but is not permeable to water, glycerol and dihydroxyacetone; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Glycerol-3-phosphate dehydrogenase,FAD-dependent. | 0.604 |
| glpF1 | glpK | lp_0108 | lp_0370 | Glycerol uptake facilitator protein; Transporter that facilitates the transmembrane diffusion of D/L-lactic acid. Is involved in the cellular racemization of lactate and lactate metabolism. The transported molecule is indeed lactic acid and not the lactate anion, in agreement with the assumption that, with very few exceptions, MIPs (major intrinsic proteins) only facilitate the transport of uncharged solutes. Also facilitates urea and H(2)O(2) diffusion across membranes, but is not permeable to water, glycerol and dihydroxyacetone; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.651 |
| glpF1 | gykA | lp_0108 | lp_0834 | Glycerol uptake facilitator protein; Transporter that facilitates the transmembrane diffusion of D/L-lactic acid. Is involved in the cellular racemization of lactate and lactate metabolism. The transported molecule is indeed lactic acid and not the lactate anion, in agreement with the assumption that, with very few exceptions, MIPs (major intrinsic proteins) only facilitate the transport of uncharged solutes. Also facilitates urea and H(2)O(2) diffusion across membranes, but is not permeable to water, glycerol and dihydroxyacetone; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. | 0.533 |
| glpF3 | glpD | lp_0372 | lp_0371 | Glycerol uptake facilitator protein; Transporter that facilitates the transmembrane diffusion of water, dihydroxyacetone, glycerol and H(2)O(2). Is not permeable to urea and D/L-lactic acid; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Glycerol-3-phosphate dehydrogenase,FAD-dependent. | 0.984 |
| glpF3 | glpK | lp_0372 | lp_0370 | Glycerol uptake facilitator protein; Transporter that facilitates the transmembrane diffusion of water, dihydroxyacetone, glycerol and H(2)O(2). Is not permeable to urea and D/L-lactic acid; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.933 |
| glpF3 | gykA | lp_0372 | lp_0834 | Glycerol uptake facilitator protein; Transporter that facilitates the transmembrane diffusion of water, dihydroxyacetone, glycerol and H(2)O(2). Is not permeable to urea and D/L-lactic acid; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. | 0.533 |
| glpF3 | pts4ABC | lp_0372 | lp_0264 | Glycerol uptake facilitator protein; Transporter that facilitates the transmembrane diffusion of water, dihydroxyacetone, glycerol and H(2)O(2). Is not permeable to urea and D/L-lactic acid; Belongs to the MIP/aquaporin (TC 1.A.8) family. | PTS system, trehalose-specific IIBC component. | 0.417 |
| glpK | dhaP | lp_0370 | lp_0171 | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | Dihydroxyacetone transport protein; Transporter that facilitates the transmembrane diffusion of water, dihydroxyacetone, glycerol and H(2)O(2). Is not permeable to urea and D/L-lactic acid; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.818 |
| glpK | glpD | lp_0370 | lp_0371 | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | Glycerol-3-phosphate dehydrogenase,FAD-dependent. | 0.998 |
| glpK | glpF1 | lp_0370 | lp_0108 | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | Glycerol uptake facilitator protein; Transporter that facilitates the transmembrane diffusion of D/L-lactic acid. Is involved in the cellular racemization of lactate and lactate metabolism. The transported molecule is indeed lactic acid and not the lactate anion, in agreement with the assumption that, with very few exceptions, MIPs (major intrinsic proteins) only facilitate the transport of uncharged solutes. Also facilitates urea and H(2)O(2) diffusion across membranes, but is not permeable to water, glycerol and dihydroxyacetone; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.651 |
| glpK | glpF3 | lp_0370 | lp_0372 | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | Glycerol uptake facilitator protein; Transporter that facilitates the transmembrane diffusion of water, dihydroxyacetone, glycerol and H(2)O(2). Is not permeable to urea and D/L-lactic acid; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.933 |