Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
plnRPlantaricin biosynthesis protein PlnR. (50 aa)    
Predicted Functional Partners:
plnL
Bacteriocin immunity protein PlnL.
  
  
 0.968
plnJ
Bacteriocin precursor peptide PlnJ.
  
  
 0.938
plnK
Bacteriocin precursor peptide PlnK.
  
  
 0.877
plnM
Bacteriocin immunity protein PlnM.
   
  
 0.680
plnC
Two-component response regulator PlnC,activator.
   
  
 0.667
plnN
Bacteriocin precursor peptide PlnN.
   
  
 0.644
plnD
Two-component response regulator PlnD,repressor.
   
  
 0.632
plnT
Hypothetical membrane protein PlnT,membrane-bound protease CAAX family.
   
  
 0.632
plnS
Plantaricin biosynthesis protein PlnS.
   
  
 0.624
plnA
Plantaricin A precursor peptide, induction factor; This heat stable bacteriocin inhibits the growth of closely related Lactobacillus species. It may act as a pore-forming protein, creating a channel in the cell membrane through a 'barrel stave' mechanism.
   
  
 0.605
Your Current Organism:
Lactobacillus plantarum
NCBI taxonomy Id: 220668
Other names: L. plantarum WCFS1, Lactobacillus plantarum WCFS1, Lactobacillus plantarum str. WCFS1, Lactobacillus plantarum strain WCFS1
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