STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobBNAD-dependent deacetylase, SIR2 family; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. (234 aa)    
Predicted Functional Partners:
gdh
Glutamate dehydrogenase, NADP-specific; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 0.980
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
 0.933
nadE
NAD synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
    
 0.926
ppnK
Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
 
 0.923
lp_3123
NADH pyrophosphatase, Nudix family.
    
 0.909
lp_2591
Purine nucleosidase.
   
 
 0.905
lp_2825
Purine nucleosidase, inosine-uridine preferring.
   
 
 0.905
mvaA
hydroxymethylglutaryl-CoA reductase; Belongs to the HMG-CoA reductase family.
  
  
 0.855
lp_0450
Hypothetical protein, DUF72 family.
  
    0.846
lp_0448
Hypothetical protein.
  
  
 0.835
Your Current Organism:
Lactobacillus plantarum
NCBI taxonomy Id: 220668
Other names: L. plantarum WCFS1, Lactobacillus plantarum WCFS1, Lactobacillus plantarum str. WCFS1, Lactobacillus plantarum strain WCFS1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.