| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| birA1 | birA2 | lp_0337 | lp_0854 | biotin-[acetyl-CoA-carboxylase] ligase and biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | biotin-[acetyl-CoA-carboxylase] ligase and biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.932 |
| birA1 | lp_0452 | lp_0337 | lp_0452 | biotin-[acetyl-CoA-carboxylase] ligase and biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Phosphohydrolase, MutT/nudix family. | 0.546 |
| birA1 | metS | lp_0337 | lp_0454 | biotin-[acetyl-CoA-carboxylase] ligase and biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | methionine-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. | 0.609 |
| birA2 | birA1 | lp_0854 | lp_0337 | biotin-[acetyl-CoA-carboxylase] ligase and biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | biotin-[acetyl-CoA-carboxylase] ligase and biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.932 |
| birA2 | lp_0452 | lp_0854 | lp_0452 | biotin-[acetyl-CoA-carboxylase] ligase and biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Phosphohydrolase, MutT/nudix family. | 0.546 |
| birA2 | metS | lp_0854 | lp_0454 | biotin-[acetyl-CoA-carboxylase] ligase and biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | methionine-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. | 0.600 |
| dapF | lp_0452 | lp_2185 | lp_0452 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Phosphohydrolase, MutT/nudix family. | 0.450 |
| lp_0452 | birA1 | lp_0452 | lp_0337 | Phosphohydrolase, MutT/nudix family. | biotin-[acetyl-CoA-carboxylase] ligase and biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.546 |
| lp_0452 | birA2 | lp_0452 | lp_0854 | Phosphohydrolase, MutT/nudix family. | biotin-[acetyl-CoA-carboxylase] ligase and biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.546 |
| lp_0452 | dapF | lp_0452 | lp_2185 | Phosphohydrolase, MutT/nudix family. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.450 |
| lp_0452 | lp_1446 | lp_0452 | lp_1446 | Phosphohydrolase, MutT/nudix family. | Cell surface protein, CscB family. | 0.583 |
| lp_0452 | metS | lp_0452 | lp_0454 | Phosphohydrolase, MutT/nudix family. | methionine-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. | 0.509 |
| lp_0452 | rhe1 | lp_0452 | lp_0520 | Phosphohydrolase, MutT/nudix family. | ATP-dependent RNA helicase; DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity; Belongs to the DEAD box helicase family. CshA subfamily. | 0.410 |
| lp_0452 | rhe2 | lp_0452 | lp_1162 | Phosphohydrolase, MutT/nudix family. | ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. | 0.410 |
| lp_0452 | rhe3 | lp_0452 | lp_2278 | Phosphohydrolase, MutT/nudix family. | ATP-dependent RNA helicase; Probable DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures. | 0.410 |
| lp_0452 | rnr | lp_0452 | lp_0797 | Phosphohydrolase, MutT/nudix family. | Exoribonuclease II; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | 0.469 |
| lp_1446 | lp_0452 | lp_1446 | lp_0452 | Cell surface protein, CscB family. | Phosphohydrolase, MutT/nudix family. | 0.583 |
| metS | birA1 | lp_0454 | lp_0337 | methionine-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. | biotin-[acetyl-CoA-carboxylase] ligase and biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.609 |
| metS | birA2 | lp_0454 | lp_0854 | methionine-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. | biotin-[acetyl-CoA-carboxylase] ligase and biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.600 |
| metS | lp_0452 | lp_0454 | lp_0452 | methionine-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. | Phosphohydrolase, MutT/nudix family. | 0.509 |