Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
sdaCSerine transporter. (426 aa)    
Predicted Functional Partners:
sdhB
L-serine dehydratase, beta subunit; Belongs to the iron-sulfur dependent L-serine dehydratase family.
  
  
 0.964
sdhA
L-serine dehydratase, alpha subunit; Belongs to the iron-sulfur dependent L-serine dehydratase family.
 
  
 0.922
serS1
serine-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).
  
  
 0.876
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
   
 0.691
lp_0557
Serine/threonine protein phosphatase.
    
   0.538
coaA
Pantothenate kinase.
  
   
 0.492
lp_1703
Diacylglycerol kinase family protein.
  
     0.482
dps1
DNA-binding ferritin-like protein, DPS family; Belongs to the Dps family.
    
   0.475
dps2
DNA-binding ferritin-like protein, DPS family; Belongs to the Dps family.
    
   0.475
lp_0507
Hypothetical protein.
 
    0.464
Your Current Organism:
Lactobacillus plantarum
NCBI taxonomy Id: 220668
Other names: L. plantarum WCFS1, Lactobacillus plantarum WCFS1, Lactobacillus plantarum str. WCFS1, Lactobacillus plantarum strain WCFS1
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