STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lp_0524Toxin-antitoxin system, toxin component DNA-binding protein, PemK/MazF family; Toxic component of a type II toxin-antitoxin (TA) system. (130 aa)    
Predicted Functional Partners:
parE
Topoisomerase IV, subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 2 subfamily.
      
 0.797
gpsB
Cell division initiation protein DivIVA; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation.
   
    0.703
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
   
  
 0.602
rpmE
50S ribosomal protein L31; Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
  
    0.562
orf6
Hypothetical protein.
      
 0.549
orf9
Hypothetical protein.
      
 0.548
orf21
Hypothetical protein.
      
 0.543
orf20
Hypothetical protein.
      
 0.542
orf8
Hypothetical protein.
      
 0.541
lp_2753
Phosphohydrolase, MutT/nudix family.
   
    0.540
Your Current Organism:
Lactobacillus plantarum
NCBI taxonomy Id: 220668
Other names: L. plantarum WCFS1, Lactobacillus plantarum WCFS1, Lactobacillus plantarum str. WCFS1, Lactobacillus plantarum strain WCFS1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.