prfB-N protein (Lactobacillus plantarum) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

prfB-N

Peptide chain release factor 2, N-terminal fragment (natural frameshift). (24 aa)

Predicted Functional Partners:

prfB-C

0.789

secA

0.543

lp_0742

0.482

rrp3

0.482

hpk3

0.482

Your Current Organism:

Lactobacillus plantarum

NCBI taxonomy Id: 220668
Other names: L. plantarum WCFS1, Lactobacillus plantarum WCFS1, Lactobacillus plantarum str. WCFS1, Lactobacillus plantarum strain WCFS1

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
hpk3	lp_0742	lp_0744	lp_0742	Two-component system histidine kinase, sensor protein, phosphate transport regulon.	Hypothetical membrane protein.	0.848
hpk3	prfB-C	lp_0744	lp_0741	Two-component system histidine kinase, sensor protein, phosphate transport regulon.	Peptide chain release factor 2, C-terminal fragment (natural frameshift); Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.	0.642
hpk3	prfB-N	lp_0744	lp_0740	Two-component system histidine kinase, sensor protein, phosphate transport regulon.	Peptide chain release factor 2, N-terminal fragment (natural frameshift).	0.482
hpk3	rrp3	lp_0744	lp_0743	Two-component system histidine kinase, sensor protein, phosphate transport regulon.	Two-component system response regulator,phosphate transport regulon.	0.997
hpk3	secA	lp_0744	lp_0739	Two-component system histidine kinase, sensor protein, phosphate transport regulon.	Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.	0.437
lp_0742	hpk3	lp_0742	lp_0744	Hypothetical membrane protein.	Two-component system histidine kinase, sensor protein, phosphate transport regulon.	0.848
lp_0742	prfB-C	lp_0742	lp_0741	Hypothetical membrane protein.	Peptide chain release factor 2, C-terminal fragment (natural frameshift); Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.	0.641
lp_0742	prfB-N	lp_0742	lp_0740	Hypothetical membrane protein.	Peptide chain release factor 2, N-terminal fragment (natural frameshift).	0.482
lp_0742	rrp3	lp_0742	lp_0743	Hypothetical membrane protein.	Two-component system response regulator,phosphate transport regulon.	0.888
lp_0742	secA	lp_0742	lp_0739	Hypothetical membrane protein.	Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.	0.474
prfB-C	hpk3	lp_0741	lp_0744	Peptide chain release factor 2, C-terminal fragment (natural frameshift); Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.	Two-component system histidine kinase, sensor protein, phosphate transport regulon.	0.642
prfB-C	lp_0742	lp_0741	lp_0742	Peptide chain release factor 2, C-terminal fragment (natural frameshift); Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.	Hypothetical membrane protein.	0.641
prfB-C	prfB-N	lp_0741	lp_0740	Peptide chain release factor 2, C-terminal fragment (natural frameshift); Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.	Peptide chain release factor 2, N-terminal fragment (natural frameshift).	0.789
prfB-C	rrp3	lp_0741	lp_0743	Peptide chain release factor 2, C-terminal fragment (natural frameshift); Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.	Two-component system response regulator,phosphate transport regulon.	0.662
prfB-C	secA	lp_0741	lp_0739	Peptide chain release factor 2, C-terminal fragment (natural frameshift); Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.	Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.	0.847
prfB-N	hpk3	lp_0740	lp_0744	Peptide chain release factor 2, N-terminal fragment (natural frameshift).	Two-component system histidine kinase, sensor protein, phosphate transport regulon.	0.482
prfB-N	lp_0742	lp_0740	lp_0742	Peptide chain release factor 2, N-terminal fragment (natural frameshift).	Hypothetical membrane protein.	0.482
prfB-N	prfB-C	lp_0740	lp_0741	Peptide chain release factor 2, N-terminal fragment (natural frameshift).	Peptide chain release factor 2, C-terminal fragment (natural frameshift); Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.	0.789
prfB-N	rrp3	lp_0740	lp_0743	Peptide chain release factor 2, N-terminal fragment (natural frameshift).	Two-component system response regulator,phosphate transport regulon.	0.482
prfB-N	secA	lp_0740	lp_0739	Peptide chain release factor 2, N-terminal fragment (natural frameshift).	Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.	0.543

page 1 of 2

Server load: low (16%) [HD]

Permalink

Network

Neighborhood

Experiments

Fusion

Databases

Co-occurrence

Textmining

Co-expression

© STRING Consortium 2026

Credits

Access

Info

About