| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| apt | gmk1 | lp_2086 | lp_1612 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.971 |
| apt | gmk2 | lp_2086 | lp_0866 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Guanylate kinase. | 0.971 |
| apt | guaA | lp_2086 | lp_0914 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | 0.991 |
| apt | hprT | lp_2086 | lp_0546 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.970 |
| apt | lp_1289 | lp_2086 | lp_1289 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Purine/pyrimidine phosphoribosyltransferase. | 0.900 |
| apt | xpt | lp_2086 | lp_1139 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.932 |
| gmk1 | apt | lp_1612 | lp_2086 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.971 |
| gmk1 | gmk2 | lp_1612 | lp_0866 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Guanylate kinase. | 0.928 |
| gmk1 | guaA | lp_1612 | lp_0914 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | 0.964 |
| gmk1 | hprT | lp_1612 | lp_0546 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.936 |
| gmk1 | lp_1289 | lp_1612 | lp_1289 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Purine/pyrimidine phosphoribosyltransferase. | 0.968 |
| gmk1 | ndk | lp_1612 | lp_0242 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Nucleoside-diphosphate kinase; Belongs to the NDK family. | 0.923 |
| gmk1 | nrdE | lp_1612 | lp_0693 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Ribonucleoside-diphosphate reductase, alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.913 |
| gmk1 | pyk | lp_1612 | lp_1897 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.947 |
| gmk1 | relA | lp_1612 | lp_1987 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | GTP pyrophosphokinase / pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.924 |
| gmk1 | xpt | lp_1612 | lp_1139 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.947 |
| gmk2 | apt | lp_0866 | lp_2086 | Guanylate kinase. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.971 |
| gmk2 | gmk1 | lp_0866 | lp_1612 | Guanylate kinase. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.928 |
| gmk2 | guaA | lp_0866 | lp_0914 | Guanylate kinase. | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | 0.956 |
| gmk2 | hprT | lp_0866 | lp_0546 | Guanylate kinase. | Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.955 |