| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| dtpT | pepM | lp_0551 | lp_0257 | Di-/tripeptide transport protein. | Methionyl aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | 0.716 |
| dtpT | pepN | lp_0551 | lp_0937 | Di-/tripeptide transport protein. | Membrane alanine aminopeptidase (aminopeptidase N). | 0.921 |
| dtpT | pepO | lp_0551 | lp_3445 | Di-/tripeptide transport protein. | Endopeptidase PepO. | 0.852 |
| dtpT | pepP | lp_0551 | lp_1595 | Di-/tripeptide transport protein. | Xaa-Pro aminopeptidase; Belongs to the peptidase M24B family. | 0.815 |
| dtpT | pepQ | lp_0551 | lp_2258 | Di-/tripeptide transport protein. | Xaa-Pro dipeptidase. | 0.771 |
| dtpT | pepT | lp_0551 | lp_1904 | Di-/tripeptide transport protein. | Tripeptidase, M20B family; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family. | 0.820 |
| dtpT | pepV | lp_0551 | lp_1321 | Di-/tripeptide transport protein. | Xaa-His dipeptidase. | 0.855 |
| dtpT | pepX | lp_0551 | lp_0857 | Di-/tripeptide transport protein. | Xaa-Pro dipeptidyl-peptidase; Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline; Belongs to the peptidase S15 family. | 0.878 |
| glyA | pepN | lp_2375 | lp_0937 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Membrane alanine aminopeptidase (aminopeptidase N). | 0.915 |
| gshAB | pepN | lp_2336 | lp_0937 | Glutathione biosynthesis bifunctional protein: glutamate-cysteine ligase; Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine; In the N-terminal section; belongs to the glutamate-- cysteine ligase type 1 family. Type 2 subfamily. | Membrane alanine aminopeptidase (aminopeptidase N). | 0.916 |
| pepM | dtpT | lp_0257 | lp_0551 | Methionyl aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | Di-/tripeptide transport protein. | 0.716 |
| pepM | pepN | lp_0257 | lp_0937 | Methionyl aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | Membrane alanine aminopeptidase (aminopeptidase N). | 0.933 |
| pepM | pepO | lp_0257 | lp_3445 | Methionyl aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | Endopeptidase PepO. | 0.806 |
| pepM | pepP | lp_0257 | lp_1595 | Methionyl aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | Xaa-Pro aminopeptidase; Belongs to the peptidase M24B family. | 0.738 |
| pepM | pepQ | lp_0257 | lp_2258 | Methionyl aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | Xaa-Pro dipeptidase. | 0.875 |
| pepM | pepT | lp_0257 | lp_1904 | Methionyl aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | Tripeptidase, M20B family; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family. | 0.890 |
| pepM | pepV | lp_0257 | lp_1321 | Methionyl aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | Xaa-His dipeptidase. | 0.911 |
| pepM | pepX | lp_0257 | lp_0857 | Methionyl aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | Xaa-Pro dipeptidyl-peptidase; Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline; Belongs to the peptidase S15 family. | 0.872 |
| pepN | dtpT | lp_0937 | lp_0551 | Membrane alanine aminopeptidase (aminopeptidase N). | Di-/tripeptide transport protein. | 0.921 |
| pepN | glyA | lp_0937 | lp_2375 | Membrane alanine aminopeptidase (aminopeptidase N). | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.915 |
