node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
acm1 | dacB | lp_1138 | lp_1010 | Cell wall hydrolase/muramidase. | Serine-type D-Ala-D-Ala carboxypeptidase. | 0.679 |
asnB1 | dacB | lp_0980 | lp_1010 | Asparagine synthase (glutamine-hydrolysing). | Serine-type D-Ala-D-Ala carboxypeptidase. | 0.704 |
asnB1 | murE1 | lp_0980 | lp_0977 | Asparagine synthase (glutamine-hydrolysing). | UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.804 |
dacA | dacA1 | lp_0818 | lp_3189 | Hypothetical membrane protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | Serine-type D-Ala-D-Ala carboxypeptidase; Belongs to the peptidase S11 family. | 0.596 |
dacA | dacB | lp_0818 | lp_1010 | Hypothetical membrane protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | Serine-type D-Ala-D-Ala carboxypeptidase. | 0.571 |
dacA | murD | lp_0818 | lp_2197 | Hypothetical membrane protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.694 |
dacA | murI | lp_0818 | lp_2268 | Hypothetical membrane protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.621 |
dacA1 | dacA | lp_3189 | lp_0818 | Serine-type D-Ala-D-Ala carboxypeptidase; Belongs to the peptidase S11 family. | Hypothetical membrane protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | 0.596 |
dacA1 | dacA2 | lp_3189 | lp_1278 | Serine-type D-Ala-D-Ala carboxypeptidase; Belongs to the peptidase S11 family. | Serine-type D-Ala-D-Ala carboxypeptidase; Belongs to the peptidase S11 family. | 0.927 |
dacA1 | dacB | lp_3189 | lp_1010 | Serine-type D-Ala-D-Ala carboxypeptidase; Belongs to the peptidase S11 family. | Serine-type D-Ala-D-Ala carboxypeptidase. | 0.950 |
dacA1 | murD | lp_3189 | lp_2197 | Serine-type D-Ala-D-Ala carboxypeptidase; Belongs to the peptidase S11 family. | UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.433 |
dacA1 | murE1 | lp_3189 | lp_0977 | Serine-type D-Ala-D-Ala carboxypeptidase; Belongs to the peptidase S11 family. | UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.503 |
dacA1 | murI | lp_3189 | lp_2268 | Serine-type D-Ala-D-Ala carboxypeptidase; Belongs to the peptidase S11 family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.485 |
dacA1 | pbp1A | lp_3189 | lp_1751 | Serine-type D-Ala-D-Ala carboxypeptidase; Belongs to the peptidase S11 family. | Transpeptidase-transglycosylase (penicillin binding protein 1A). | 0.940 |
dacA1 | pbp2A | lp_3189 | lp_1413 | Serine-type D-Ala-D-Ala carboxypeptidase; Belongs to the peptidase S11 family. | Transpeptidase-transglycosylase (penicillin binding protein 2A). | 0.934 |
dacA2 | dacA1 | lp_1278 | lp_3189 | Serine-type D-Ala-D-Ala carboxypeptidase; Belongs to the peptidase S11 family. | Serine-type D-Ala-D-Ala carboxypeptidase; Belongs to the peptidase S11 family. | 0.927 |
dacA2 | dacB | lp_1278 | lp_1010 | Serine-type D-Ala-D-Ala carboxypeptidase; Belongs to the peptidase S11 family. | Serine-type D-Ala-D-Ala carboxypeptidase. | 0.914 |
dacA2 | pbp1A | lp_1278 | lp_1751 | Serine-type D-Ala-D-Ala carboxypeptidase; Belongs to the peptidase S11 family. | Transpeptidase-transglycosylase (penicillin binding protein 1A). | 0.942 |
dacA2 | pbp2A | lp_1278 | lp_1413 | Serine-type D-Ala-D-Ala carboxypeptidase; Belongs to the peptidase S11 family. | Transpeptidase-transglycosylase (penicillin binding protein 2A). | 0.929 |
dacB | acm1 | lp_1010 | lp_1138 | Serine-type D-Ala-D-Ala carboxypeptidase. | Cell wall hydrolase/muramidase. | 0.679 |