| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| fum | lp_1113 | lp_1112 | lp_1113 | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | Fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.998 |
| fum | lp_3491 | lp_1112 | lp_3491 | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | Fumarate reductase, flavoprotein subunit precursor. | 0.967 |
| fum | mae | lp_1112 | lp_1105 | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | Malic enzyme, NAD-dependent. | 0.962 |
| fum | mleS | lp_1112 | lp_1118 | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | Malolactic enzyme; Involved in the malolactic fermentation (MLF) of wine, which results in a natural decrease in acidity and favorable changes in wine flavors. Catalyzes the decarboxylation of L-malate to L-lactate. Belongs to the malic enzymes family. | 0.954 |
| fum | pycA | lp_1112 | lp_2136 | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.501 |
| fum | ttdA | lp_1112 | lp_1090 | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | L(+)-tartrate dehydratase, subunit A. | 0.883 |
| fum | ttdB | lp_1112 | lp_1089 | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | L(+)-tartrate dehydratase, subunit B. | 0.882 |
| lp_1113 | fum | lp_1113 | lp_1112 | Fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.998 |
| lp_1113 | lp_3491 | lp_1113 | lp_3491 | Fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | Fumarate reductase, flavoprotein subunit precursor. | 0.941 |
| lp_1113 | mae | lp_1113 | lp_1105 | Fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | Malic enzyme, NAD-dependent. | 0.589 |
| lp_1113 | ttdA | lp_1113 | lp_1090 | Fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | L(+)-tartrate dehydratase, subunit A. | 0.896 |
| lp_1113 | ttdB | lp_1113 | lp_1089 | Fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | L(+)-tartrate dehydratase, subunit B. | 0.492 |
| lp_3491 | fum | lp_3491 | lp_1112 | Fumarate reductase, flavoprotein subunit precursor. | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.967 |
| lp_3491 | lp_1113 | lp_3491 | lp_1113 | Fumarate reductase, flavoprotein subunit precursor. | Fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.941 |
| lp_3491 | ttdA | lp_3491 | lp_1090 | Fumarate reductase, flavoprotein subunit precursor. | L(+)-tartrate dehydratase, subunit A. | 0.842 |
| lp_3491 | ttdB | lp_3491 | lp_1089 | Fumarate reductase, flavoprotein subunit precursor. | L(+)-tartrate dehydratase, subunit B. | 0.487 |
| mae | fum | lp_1105 | lp_1112 | Malic enzyme, NAD-dependent. | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.962 |
| mae | lp_1113 | lp_1105 | lp_1113 | Malic enzyme, NAD-dependent. | Fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.589 |
| mae | mleS | lp_1105 | lp_1118 | Malic enzyme, NAD-dependent. | Malolactic enzyme; Involved in the malolactic fermentation (MLF) of wine, which results in a natural decrease in acidity and favorable changes in wine flavors. Catalyzes the decarboxylation of L-malate to L-lactate. Belongs to the malic enzymes family. | 0.921 |
| mae | pck | lp_1105 | lp_3418 | Malic enzyme, NAD-dependent. | Phosphoenolpyruvate carboxykinase (ATP). | 0.512 |