STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
fumFumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (460 aa)    
Predicted Functional Partners:
lp_1113
Fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
 
 0.998
lp_3491
Fumarate reductase, flavoprotein subunit precursor.
  
 0.967
mae
Malic enzyme, NAD-dependent.
  
 
 0.962
mleS
Malolactic enzyme; Involved in the malolactic fermentation (MLF) of wine, which results in a natural decrease in acidity and favorable changes in wine flavors. Catalyzes the decarboxylation of L-malate to L-lactate. Belongs to the malic enzymes family.
  
 
 0.954
ttdA
L(+)-tartrate dehydratase, subunit A.
  
 
 0.883
ttdB
L(+)-tartrate dehydratase, subunit B.
  
 
 0.882
gabD
Succinate-semialdehyde dehydrogenase (NAD(P)+).
   
 0.847
ldhL2
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate.
  
 
 0.842
argH
Argininosuccinate lyase.
   
 
 0.834
adhE
Bifunctional protein: alcohol dehydrogenase; acetaldehyde dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
   
 
 0.724
Your Current Organism:
Lactobacillus plantarum
NCBI taxonomy Id: 220668
Other names: L. plantarum WCFS1, Lactobacillus plantarum WCFS1, Lactobacillus plantarum str. WCFS1, Lactobacillus plantarum strain WCFS1
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