STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dacA2Serine-type D-Ala-D-Ala carboxypeptidase; Belongs to the peptidase S11 family. (412 aa)    
Predicted Functional Partners:
pbp1A
Transpeptidase-transglycosylase (penicillin binding protein 1A).
 
 
 0.942
pbp2A
Transpeptidase-transglycosylase (penicillin binding protein 2A).
 
 
 0.929
dacA1
Serine-type D-Ala-D-Ala carboxypeptidase; Belongs to the peptidase S11 family.
 
  
 
0.927
dacB
Serine-type D-Ala-D-Ala carboxypeptidase.
   
 
 0.914
mprF-2
Hypothetical membrane protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
  
  
 0.626
lp_1276
Glucosyl-diacylglycerol 6-beta-glucosyltransferase.
  
  
 0.614
tig
Trigger factor / peptidylprolyl isomerase; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.
  
    0.511
ctpA
Carboxy-terminal proteinase, S41 family,peptidoglycan-bound; Belongs to the peptidase S41A family.
 
 
 0.501
greA2
Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.
 
     0.464
lp_1275
1,2-diacylglycerol 3-glucosyltransferase.
  
  
 0.458
Your Current Organism:
Lactobacillus plantarum
NCBI taxonomy Id: 220668
Other names: L. plantarum WCFS1, Lactobacillus plantarum WCFS1, Lactobacillus plantarum str. WCFS1, Lactobacillus plantarum strain WCFS1
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