| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| hprK | pdhA | lp_0754 | lp_2154 | Bifunctional protein: HPr kinase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisabl [...] | Pyruvate dehydrogenase complex, E1 component,alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). | 0.403 |
| hprK | pdhC | lp_0754 | lp_2152 | Bifunctional protein: HPr kinase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisabl [...] | Pyruvate dehydrogenase complex, E2 component; dihydrolipoamide S-acetyltransferase. | 0.422 |
| hprK | pgm5 | lp_0754 | lp_1785 | Bifunctional protein: HPr kinase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisabl [...] | Phosphoglycerate mutase family protein; Belongs to the phosphoglycerate mutase family. | 0.569 |
| hprK | serC | lp_0754 | lp_0204 | Bifunctional protein: HPr kinase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisabl [...] | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | 0.471 |
| hprK | tkt4 | lp_0754 | lp_3538 | Bifunctional protein: HPr kinase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisabl [...] | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | 0.409 |
| lp_0862 | pgm5 | lp_0862 | lp_1785 | Hypothetical protein. | Phosphoglycerate mutase family protein; Belongs to the phosphoglycerate mutase family. | 0.516 |
| pdhA | hprK | lp_2154 | lp_0754 | Pyruvate dehydrogenase complex, E1 component,alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). | Bifunctional protein: HPr kinase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisabl [...] | 0.403 |
| pdhA | pdhB | lp_2154 | lp_2153 | Pyruvate dehydrogenase complex, E1 component,alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). | Pyruvate dehydrogenase complex, E1 component,beta subunit. | 0.999 |
| pdhA | pdhC | lp_2154 | lp_2152 | Pyruvate dehydrogenase complex, E1 component,alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). | Pyruvate dehydrogenase complex, E2 component; dihydrolipoamide S-acetyltransferase. | 0.999 |
| pdhA | pgm5 | lp_2154 | lp_1785 | Pyruvate dehydrogenase complex, E1 component,alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). | Phosphoglycerate mutase family protein; Belongs to the phosphoglycerate mutase family. | 0.525 |
| pdhA | tkt4 | lp_2154 | lp_3538 | Pyruvate dehydrogenase complex, E1 component,alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | 0.851 |
| pdhB | pdhA | lp_2153 | lp_2154 | Pyruvate dehydrogenase complex, E1 component,beta subunit. | Pyruvate dehydrogenase complex, E1 component,alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). | 0.999 |
| pdhB | pdhC | lp_2153 | lp_2152 | Pyruvate dehydrogenase complex, E1 component,beta subunit. | Pyruvate dehydrogenase complex, E2 component; dihydrolipoamide S-acetyltransferase. | 0.999 |
| pdhB | pgm5 | lp_2153 | lp_1785 | Pyruvate dehydrogenase complex, E1 component,beta subunit. | Phosphoglycerate mutase family protein; Belongs to the phosphoglycerate mutase family. | 0.561 |
| pdhB | tkt4 | lp_2153 | lp_3538 | Pyruvate dehydrogenase complex, E1 component,beta subunit. | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | 0.858 |
| pdhC | hprK | lp_2152 | lp_0754 | Pyruvate dehydrogenase complex, E2 component; dihydrolipoamide S-acetyltransferase. | Bifunctional protein: HPr kinase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisabl [...] | 0.422 |
| pdhC | pdhA | lp_2152 | lp_2154 | Pyruvate dehydrogenase complex, E2 component; dihydrolipoamide S-acetyltransferase. | Pyruvate dehydrogenase complex, E1 component,alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). | 0.999 |
| pdhC | pdhB | lp_2152 | lp_2153 | Pyruvate dehydrogenase complex, E2 component; dihydrolipoamide S-acetyltransferase. | Pyruvate dehydrogenase complex, E1 component,beta subunit. | 0.999 |
| pdhC | pgm5 | lp_2152 | lp_1785 | Pyruvate dehydrogenase complex, E2 component; dihydrolipoamide S-acetyltransferase. | Phosphoglycerate mutase family protein; Belongs to the phosphoglycerate mutase family. | 0.520 |
| pdhC | tkt4 | lp_2152 | lp_3538 | Pyruvate dehydrogenase complex, E2 component; dihydrolipoamide S-acetyltransferase. | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | 0.403 |