Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
lp_1975Short-chain dehydrogenase/oxidoreductase. (241 aa)    
Predicted Functional Partners:
nfo
Deoxyribonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
  
    0.622
lp_2568
Short-chain dehydrogenase/oxidoreductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 
 0.526
lp_0381
Ankyrin repeat family protein.
   
 0.507
hpk2
Two-component system histidine protein kinase; sensor protein.
  
 
 0.472
lp_0163
acyl-CoA dehydrogenase domain protein.
   
 0.451
lp_2914
Hypothetical membrane protein, DUF2207 family.
  
    0.450
ppiB
Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
   
 
 0.447
lp_3161
Hypothetical protein.
 
    0.437
lp_2569
Hypothetical protein.
  
    0.429
tagB3
Glycosyl/glycerophosphate transferase, teichoic acid biosynthesis protein B precursor.
  
    0.425
Your Current Organism:
Lactobacillus plantarum
NCBI taxonomy Id: 220668
Other names: L. plantarum WCFS1, Lactobacillus plantarum WCFS1, Lactobacillus plantarum str. WCFS1, Lactobacillus plantarum strain WCFS1
Server load: medium (50%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.