| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cggR | fruR | lp_0788 | lp_2095 | Central glycolytic genes regulator. | Transcription regulator, DeoR family, fructose operon. | 0.528 |
| fruA | fruK | lp_2097 | lp_2096 | PTS system, fructose-specific EIIABC component. | 1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. | 0.999 |
| fruA | fruR | lp_2097 | lp_2095 | PTS system, fructose-specific EIIABC component. | Transcription regulator, DeoR family, fructose operon. | 0.991 |
| fruA | mtlR | lp_2097 | lp_0231 | PTS system, fructose-specific EIIABC component. | Transcription regulator, BglG family, mannitol operon. | 0.862 |
| fruA | pts11A | lp_2097 | lp_0884 | PTS system, fructose-specific EIIABC component. | PTS system, EIIA component. | 0.662 |
| fruA | pts11BC | lp_2097 | lp_0886 | PTS system, fructose-specific EIIABC component. | PTS system, beta-glucosides-specific EIIBC component. | 0.906 |
| fruA | pts26BCA | lp_2097 | lp_3219 | PTS system, fructose-specific EIIABC component. | PTS system, sucrose-specific EIIBCA component. | 0.963 |
| fruA | pts31A | lp_2097 | lp_3519 | PTS system, fructose-specific EIIABC component. | PTS system fructose-specific EIIA component. | 0.638 |
| fruA | pts9C | lp_2097 | lp_0576 | PTS system, fructose-specific EIIABC component. | PTS system, mannose-specific EIIC component. | 0.760 |
| fruK | fruA | lp_2096 | lp_2097 | 1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. | PTS system, fructose-specific EIIABC component. | 0.999 |
| fruK | fruR | lp_2096 | lp_2095 | 1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. | Transcription regulator, DeoR family, fructose operon. | 0.997 |
| fruK | mtlR | lp_2096 | lp_0231 | 1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. | Transcription regulator, BglG family, mannitol operon. | 0.765 |
| fruK | pts11A | lp_2096 | lp_0884 | 1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. | PTS system, EIIA component. | 0.457 |
| fruK | pts11BC | lp_2096 | lp_0886 | 1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. | PTS system, beta-glucosides-specific EIIBC component. | 0.479 |
| fruK | pts17A | lp_2096 | lp_2218 | 1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. | PTS system, glucitol/sorbitol-specific EIIA component. | 0.507 |
| fruK | pts26BCA | lp_2096 | lp_3219 | 1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. | PTS system, sucrose-specific EIIBCA component. | 0.533 |
| fruK | pts31A | lp_2096 | lp_3519 | 1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. | PTS system fructose-specific EIIA component. | 0.857 |
| fruK | pts9C | lp_2096 | lp_0576 | 1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. | PTS system, mannose-specific EIIC component. | 0.484 |
| fruR | cggR | lp_2095 | lp_0788 | Transcription regulator, DeoR family, fructose operon. | Central glycolytic genes regulator. | 0.528 |
| fruR | fruA | lp_2095 | lp_2097 | Transcription regulator, DeoR family, fructose operon. | PTS system, fructose-specific EIIABC component. | 0.991 |