STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdhDPyruvate dehydrogenase complex, E3 component; dihydrolipoamide dehydrogenase. (470 aa)    
Predicted Functional Partners:
pdhC
Pyruvate dehydrogenase complex, E2 component; dihydrolipoamide S-acetyltransferase.
 0.999
pdhB
Pyruvate dehydrogenase complex, E1 component,beta subunit.
 0.999
pdhA
Pyruvate dehydrogenase complex, E1 component,alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
 
 0.999
gcsH2
Glycine cleavage system, H protein.
 
 
 0.951
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 0.918
pflB
Formate C-acetyltransferase.
   
 
 0.917
pflF
Formate C-acetyltransferase.
     
 0.911
gdh
Glutamate dehydrogenase, NADP-specific; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.866
glnA
Glutamate-ammonia ligase.
  
 
 0.836
gadB
Glutamate decarboxylase; Belongs to the group II decarboxylase family.
   
 
 0.816
Your Current Organism:
Lactobacillus plantarum
NCBI taxonomy Id: 220668
Other names: L. plantarum WCFS1, Lactobacillus plantarum WCFS1, Lactobacillus plantarum str. WCFS1, Lactobacillus plantarum strain WCFS1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.