STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdhBPyruvate dehydrogenase complex, E1 component,beta subunit. (325 aa)    
Predicted Functional Partners:
pdhD
Pyruvate dehydrogenase complex, E3 component; dihydrolipoamide dehydrogenase.
 0.999
pdhC
Pyruvate dehydrogenase complex, E2 component; dihydrolipoamide S-acetyltransferase.
 0.999
pdhA
Pyruvate dehydrogenase complex, E1 component,alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
 0.999
pflB
Formate C-acetyltransferase.
   
 
 0.974
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.959
mae
Malic enzyme, NAD-dependent.
  
 
 0.955
pox5
Pyruvate oxidase; Important for the aerobic growth. Decarboxylates pyruvate in four steps. The energy released is partially stored in acetyl phosphate.
  
 
 0.936
ldhL2
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate.
   
 0.933
pycA
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
  
 
 0.930
hicD1
L-2-hydroxyisocaproate dehydrogenase; Belongs to the LDH/MDH superfamily.
   
 0.927
Your Current Organism:
Lactobacillus plantarum
NCBI taxonomy Id: 220668
Other names: L. plantarum WCFS1, Lactobacillus plantarum WCFS1, Lactobacillus plantarum str. WCFS1, Lactobacillus plantarum strain WCFS1
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