| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cobB | lp_3123 | lp_0449 | lp_3123 | NAD-dependent deacetylase, SIR2 family; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. | NADH pyrophosphatase, Nudix family. | 0.909 |
| cobB | nadD | lp_0449 | lp_1530 | NAD-dependent deacetylase, SIR2 family; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.933 |
| cobB | nadE | lp_0449 | lp_0566 | NAD-dependent deacetylase, SIR2 family; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. | NAD synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.926 |
| cobB | ppnK | lp_0449 | lp_2222 | NAD-dependent deacetylase, SIR2 family; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.923 |
| lp_1603 | ppnK | lp_1603 | lp_2222 | rRNA methylase. | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.572 |
| lp_2223 | lp_2224 | lp_2223 | lp_2224 | GTP pyrophosphokinase. | Dithiol-disulfide isomerase, DsbA family,FrnE-like subfamily. | 0.641 |
| lp_2223 | ppnK | lp_2223 | lp_2222 | GTP pyrophosphokinase. | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.926 |
| lp_2223 | ppx3 | lp_2223 | lp_0843 | GTP pyrophosphokinase. | Exopolyphosphatase. | 0.902 |
| lp_2223 | rluD2 | lp_2223 | lp_2221 | GTP pyrophosphokinase. | Pseudouridylate synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.850 |
| lp_2224 | lp_2223 | lp_2224 | lp_2223 | Dithiol-disulfide isomerase, DsbA family,FrnE-like subfamily. | GTP pyrophosphokinase. | 0.641 |
| lp_2224 | ppnK | lp_2224 | lp_2222 | Dithiol-disulfide isomerase, DsbA family,FrnE-like subfamily. | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.641 |
| lp_2224 | rluD2 | lp_2224 | lp_2221 | Dithiol-disulfide isomerase, DsbA family,FrnE-like subfamily. | Pseudouridylate synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.633 |
| lp_3123 | cobB | lp_3123 | lp_0449 | NADH pyrophosphatase, Nudix family. | NAD-dependent deacetylase, SIR2 family; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. | 0.909 |
| lp_3123 | nadD | lp_3123 | lp_1530 | NADH pyrophosphatase, Nudix family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.907 |
| lp_3123 | nadE | lp_3123 | lp_0566 | NADH pyrophosphatase, Nudix family. | NAD synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.909 |
| lp_3123 | ppnK | lp_3123 | lp_2222 | NADH pyrophosphatase, Nudix family. | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.905 |
| nadD | cobB | lp_1530 | lp_0449 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | NAD-dependent deacetylase, SIR2 family; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. | 0.933 |
| nadD | lp_3123 | lp_1530 | lp_3123 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | NADH pyrophosphatase, Nudix family. | 0.907 |
| nadD | nadE | lp_1530 | lp_0566 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | NAD synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.951 |
| nadD | ppnK | lp_1530 | lp_2222 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.940 |