STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lp_2224Dithiol-disulfide isomerase, DsbA family,FrnE-like subfamily. (211 aa)    
Predicted Functional Partners:
spx1
RNA polymerase (RNAP)-binding regulatory protein, arsenate reductase (ArsC) family, Spx subfamily; Belongs to the ArsC family.
  
 
 0.782
mecA
Negative regulator of competence; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
  
  
 0.769
spx3
RNA polymerase (RNAP)-binding regulatory protein, arsenate reductase (ArsC) family, Spx subfamily; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress. Belongs to the ArsC family. Spx subfamily.
  
 
 0.747
spx4
RNA polymerase (RNAP)-binding regulatory protein, arsenate reductase (ArsC) family, Spx subfamily; Belongs to the ArsC family.
  
 
 0.721
lp_0865
Hypothetical protein.
   
    0.717
spx5
RNA polymerase (RNAP)-binding regulatory protein, arsenate reductase (ArsC) family, Spx subfamily; Belongs to the ArsC family.
  
 
 0.710
mreD
Cell shape determining protein MreD.
  
     0.680
spx2
RNA polymerase (RNAP)-binding regulatory protein, arsenate reductase (ArsC) family, Spx subfamily; Belongs to the ArsC family.
  
 
 0.663
lp_0030
Pyridoxamine 5'-phosphate oxidase family protein, FMN-binding.
   
  
 0.658
lp_3022
Hypothetical protein.
   
  
 0.653
Your Current Organism:
Lactobacillus plantarum
NCBI taxonomy Id: 220668
Other names: L. plantarum WCFS1, Lactobacillus plantarum WCFS1, Lactobacillus plantarum str. WCFS1, Lactobacillus plantarum strain WCFS1
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