STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lp_2261Hypothetical protein, DUF948 family. (138 aa)    
Predicted Functional Partners:
lp_2260
Extracellular protein, DUF336 family.
  
    0.946
ezrA
Septation ring formation regulator; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family.
  
    0.764
lp_2262
Mechanosensitive ion channel family protein.
 
    0.736
lp_2273
Hypothetical protein, DUF1292 family; Belongs to the UPF0473 family.
 
    0.704
mecA
Negative regulator of competence; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
  
    0.675
lp_2179
Cysteine desulfurase associated protein,DUF1831 family.
  
    0.672
rpoE
DNA-directed RNA polymerase, delta subunit; Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; Belongs to the RpoE family.
  
    0.651
lp_1456
ABC transporter, permease protein.
  
    0.634
lp_2236
Hypothetical protein, DUF1027 family.
  
    0.628
lp_3195
Hypothetical membrane protein, DUF1129 family.
  
    0.627
Your Current Organism:
Lactobacillus plantarum
NCBI taxonomy Id: 220668
Other names: L. plantarum WCFS1, Lactobacillus plantarum WCFS1, Lactobacillus plantarum str. WCFS1, Lactobacillus plantarum strain WCFS1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.