STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lp_2269Hypothetical protein, DUF2507 family. (227 aa)    
Predicted Functional Partners:
lp_2589
Polyphosphate:nucleotide phosphotransferase,PPK2 family.
   
    0.711
murI
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
  
    0.698
lp_2883
Hypothetical protein.
   
    0.686
lp_2266
Phosphoesterase.
       0.682
lp_2265
CBS domain-containing protein.
 
     0.676
xtp1
Xanthosine triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
       0.666
lp_1891
Hypothetical protein.
  
    0.598
lp_1146
Lipoprotein, pheromone precursor.
  
     0.574
lp_0742
Hypothetical membrane protein.
  
    0.565
lp_0946
Mucus-binding protein, LPXTG-motif cell wall anchor.
  
     0.545
Your Current Organism:
Lactobacillus plantarum
NCBI taxonomy Id: 220668
Other names: L. plantarum WCFS1, Lactobacillus plantarum WCFS1, Lactobacillus plantarum str. WCFS1, Lactobacillus plantarum strain WCFS1
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