STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pflFFormate C-acetyltransferase. (814 aa)    
Predicted Functional Partners:
pflE
Formate acetyltransferase activating enzyme.
  
 0.985
adhE
Bifunctional protein: alcohol dehydrogenase; acetaldehyde dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 
 0.965
pflA
Formate C-acetyltransferase activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.
  
 0.953
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.940
pta
Phosphate acetyltransferase.
   
 
 0.939
ldhL1
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate.
   
 
 0.927
ldhL2
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate.
   
 
 0.923
pox1
Pyruvate oxidase; Belongs to the TPP enzyme family.
     
 0.922
pox3
Pyruvate oxidase; Belongs to the TPP enzyme family.
     
 0.922
pox5
Pyruvate oxidase; Important for the aerobic growth. Decarboxylates pyruvate in four steps. The energy released is partially stored in acetyl phosphate.
     
 0.921
Your Current Organism:
Lactobacillus plantarum
NCBI taxonomy Id: 220668
Other names: L. plantarum WCFS1, Lactobacillus plantarum WCFS1, Lactobacillus plantarum str. WCFS1, Lactobacillus plantarum strain WCFS1
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