STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nrdIRibonucleotide reductase protein NrdI; Belongs to the NrdI family. (161 aa)    
Predicted Functional Partners:
nrdF
Ribonucleoside-diphosphate reductase, beta chain.
 
 
 0.998
nrdE
Ribonucleoside-diphosphate reductase, alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
 
  
 0.994
nrdH
Glutaredoxin-like protein nrdH.
 
  
 0.965
nrdG
Anaerobic ribonucleotide reductase activator protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
     
 0.747
nrdR
Transcription regulator NrdR, ATP cone family; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.
   
  
 0.730
lp_0996
Metal-dependent regulator.
   
  
 0.724
lp_1412
Hypothetical protein.
   
  
 0.715
nrdD
Anaerobic ribonucleoside-triphosphate reductase.
     
 0.635
lp_2671
Transport protein with CBS domains, DUF21 family.
  
  
 0.579
lp_0448
Hypothetical protein.
  
     0.537
Your Current Organism:
Lactobacillus plantarum
NCBI taxonomy Id: 220668
Other names: L. plantarum WCFS1, Lactobacillus plantarum WCFS1, Lactobacillus plantarum str. WCFS1, Lactobacillus plantarum strain WCFS1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.