| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| carB | purF | lp_0526 | lp_2723 | Carbamoyl-phosphate synthase, large subunit. | Amidophosphoribosyltransferase precursor; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.953 |
| carB | pyrAA | lp_0526 | lp_2701 | Carbamoyl-phosphate synthase, large subunit. | Carbamoyl-phosphate synthase,pyrimidine-specific, small chain; Belongs to the CarA family. | 0.999 |
| carB | pyrAA2 | lp_0526 | lp_1783 | Carbamoyl-phosphate synthase, large subunit. | Carbamoyl-phosphate synthase (glutamine-hydrolysing), small chain; Belongs to the CarA family. | 0.999 |
| carB | pyrAB | lp_0526 | lp_2700 | Carbamoyl-phosphate synthase, large subunit. | Carbamoyl-phosphate synthase,pyrimidine-specific, large chain. | 0.903 |
| carB | pyrB | lp_0526 | lp_2703 | Carbamoyl-phosphate synthase, large subunit. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
| carB | pyrC | lp_0526 | lp_2702 | Carbamoyl-phosphate synthase, large subunit. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.996 |
| carB | pyrD | lp_0526 | lp_2699 | Carbamoyl-phosphate synthase, large subunit. | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily. | 0.881 |
| carB | pyrE | lp_0526 | lp_2697 | Carbamoyl-phosphate synthase, large subunit. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.907 |
| carB | pyrF | lp_0526 | lp_2698 | Carbamoyl-phosphate synthase, large subunit. | Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.935 |
| purF | carB | lp_2723 | lp_0526 | Amidophosphoribosyltransferase precursor; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | Carbamoyl-phosphate synthase, large subunit. | 0.953 |
| purF | pyrAA | lp_2723 | lp_2701 | Amidophosphoribosyltransferase precursor; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | Carbamoyl-phosphate synthase,pyrimidine-specific, small chain; Belongs to the CarA family. | 0.943 |
| purF | pyrAA2 | lp_2723 | lp_1783 | Amidophosphoribosyltransferase precursor; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | Carbamoyl-phosphate synthase (glutamine-hydrolysing), small chain; Belongs to the CarA family. | 0.943 |
| purF | pyrAB | lp_2723 | lp_2700 | Amidophosphoribosyltransferase precursor; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | Carbamoyl-phosphate synthase,pyrimidine-specific, large chain. | 0.948 |
| purF | pyrAB2 | lp_2723 | lp_1784 | Amidophosphoribosyltransferase precursor; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | Carbamoyl-phosphate synthase (glutamine-hydrolysing), large chain; Belongs to the CarB family. | 0.503 |
| purF | pyrB | lp_2723 | lp_2703 | Amidophosphoribosyltransferase precursor; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.538 |
| purF | pyrC | lp_2723 | lp_2702 | Amidophosphoribosyltransferase precursor; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.470 |
| purF | pyrD | lp_2723 | lp_2699 | Amidophosphoribosyltransferase precursor; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily. | 0.796 |
| purF | pyrE | lp_2723 | lp_2697 | Amidophosphoribosyltransferase precursor; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.610 |
| pyrAA | carB | lp_2701 | lp_0526 | Carbamoyl-phosphate synthase,pyrimidine-specific, small chain; Belongs to the CarA family. | Carbamoyl-phosphate synthase, large subunit. | 0.999 |
| pyrAA | purF | lp_2701 | lp_2723 | Carbamoyl-phosphate synthase,pyrimidine-specific, small chain; Belongs to the CarA family. | Amidophosphoribosyltransferase precursor; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.943 |