node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
carA | carB | lp_0527 | lp_0526 | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Carbamoyl-phosphate synthase, large subunit. | 0.999 |
carA | pyrAA | lp_0527 | lp_2701 | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Carbamoyl-phosphate synthase,pyrimidine-specific, small chain; Belongs to the CarA family. | 0.914 |
carA | pyrAA2 | lp_0527 | lp_1783 | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Carbamoyl-phosphate synthase (glutamine-hydrolysing), small chain; Belongs to the CarA family. | 0.913 |
carA | pyrAB | lp_0527 | lp_2700 | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Carbamoyl-phosphate synthase,pyrimidine-specific, large chain. | 0.999 |
carA | pyrB | lp_0527 | lp_2703 | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
carA | pyrC | lp_0527 | lp_2702 | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.993 |
carA | pyrD | lp_0527 | lp_2699 | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily. | 0.782 |
carA | pyrE | lp_0527 | lp_2697 | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.770 |
carA | pyrF | lp_0527 | lp_2698 | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.870 |
carA | pyrR1 | lp_0527 | lp_2704 | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Pyrimidine operon regulator; Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes (Probable). Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. | 0.741 |
carB | carA | lp_0526 | lp_0527 | Carbamoyl-phosphate synthase, large subunit. | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | 0.999 |
carB | pyrAA | lp_0526 | lp_2701 | Carbamoyl-phosphate synthase, large subunit. | Carbamoyl-phosphate synthase,pyrimidine-specific, small chain; Belongs to the CarA family. | 0.999 |
carB | pyrAA2 | lp_0526 | lp_1783 | Carbamoyl-phosphate synthase, large subunit. | Carbamoyl-phosphate synthase (glutamine-hydrolysing), small chain; Belongs to the CarA family. | 0.999 |
carB | pyrAB | lp_0526 | lp_2700 | Carbamoyl-phosphate synthase, large subunit. | Carbamoyl-phosphate synthase,pyrimidine-specific, large chain. | 0.903 |
carB | pyrB | lp_0526 | lp_2703 | Carbamoyl-phosphate synthase, large subunit. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
carB | pyrC | lp_0526 | lp_2702 | Carbamoyl-phosphate synthase, large subunit. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.996 |
carB | pyrD | lp_0526 | lp_2699 | Carbamoyl-phosphate synthase, large subunit. | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily. | 0.881 |
carB | pyrE | lp_0526 | lp_2697 | Carbamoyl-phosphate synthase, large subunit. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.907 |
carB | pyrF | lp_0526 | lp_2698 | Carbamoyl-phosphate synthase, large subunit. | Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.935 |
carB | pyrR1 | lp_0526 | lp_2704 | Carbamoyl-phosphate synthase, large subunit. | Pyrimidine operon regulator; Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes (Probable). Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. | 0.742 |