| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| hdhD1 | lp_2954 | lp_2532 | lp_2954 | D-2-hydroxyacid dehydrogenase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | Hypothetical membrane protein. | 0.656 |
| hdhD1 | lp_3666 | lp_2532 | lp_3666 | D-2-hydroxyacid dehydrogenase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | Aromatic compound hydratase/decarboxylase. | 0.654 |
| hdhD1 | panE | lp_2532 | lp_2788 | D-2-hydroxyacid dehydrogenase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.909 |
| hdhD1 | rluD1 | lp_2532 | lp_1781 | D-2-hydroxyacid dehydrogenase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | RNA pseudouridylate synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.742 |
| hdhD1 | trpS | lp_2532 | lp_0434 | D-2-hydroxyacid dehydrogenase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | tryptophan-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.754 |
| lp_2789 | panE | lp_2789 | lp_2788 | Drug/metabolite transport protein, DMT family. | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.824 |
| lp_2954 | hdhD1 | lp_2954 | lp_2532 | Hypothetical membrane protein. | D-2-hydroxyacid dehydrogenase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.656 |
| lp_2954 | lp_3666 | lp_2954 | lp_3666 | Hypothetical membrane protein. | Aromatic compound hydratase/decarboxylase. | 0.520 |
| lp_2954 | panE | lp_2954 | lp_2788 | Hypothetical membrane protein. | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.644 |
| lp_3666 | hdhD1 | lp_3666 | lp_2532 | Aromatic compound hydratase/decarboxylase. | D-2-hydroxyacid dehydrogenase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.654 |
| lp_3666 | lp_2954 | lp_3666 | lp_2954 | Aromatic compound hydratase/decarboxylase. | Hypothetical membrane protein. | 0.520 |
| lp_3666 | panE | lp_3666 | lp_2788 | Aromatic compound hydratase/decarboxylase. | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.685 |
| moaA | panE | lp_1480 | lp_2788 | Molybdopterin precursor synthase MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.644 |
| panE | hdhD1 | lp_2788 | lp_2532 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | D-2-hydroxyacid dehydrogenase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.909 |
| panE | lp_2789 | lp_2788 | lp_2789 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | Drug/metabolite transport protein, DMT family. | 0.824 |
| panE | lp_2954 | lp_2788 | lp_2954 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | Hypothetical membrane protein. | 0.644 |
| panE | lp_3666 | lp_2788 | lp_3666 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | Aromatic compound hydratase/decarboxylase. | 0.685 |
| panE | moaA | lp_2788 | lp_1480 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | Molybdopterin precursor synthase MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.644 |
| panE | pyrAB | lp_2788 | lp_2700 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | Carbamoyl-phosphate synthase,pyrimidine-specific, large chain. | 0.644 |
| panE | pyrE | lp_2788 | lp_2697 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.601 |