| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ffh | lspA | lp_1635 | lp_1780 | Signal recognition particle protein Ffh; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Signal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | 0.583 |
| ffh | secA | lp_1635 | lp_0739 | Signal recognition particle protein Ffh; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.992 |
| ffh | secE | lp_1635 | lp_0616 | Signal recognition particle protein Ffh; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Preprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.990 |
| ffh | secG | lp_1635 | lp_0795 | Signal recognition particle protein Ffh; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.982 |
| ffh | sip1 | lp_1635 | lp_2862 | Signal recognition particle protein Ffh; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Signal peptidase I; Belongs to the peptidase S26 family. | 0.482 |
| ffh | sip2 | lp_1635 | lp_2863 | Signal recognition particle protein Ffh; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Signal peptidase I; Belongs to the peptidase S26 family. | 0.621 |
| ffh | sip3 | lp_1635 | lp_3675 | Signal recognition particle protein Ffh; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Signal peptidase I; Belongs to the peptidase S26 family. | 0.621 |
| ffh | yajC | lp_1635 | lp_2281 | Signal recognition particle protein Ffh; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Preprotein translocase, YajC subunit. | 0.982 |
| ica1 | lp_0946 | lp_1524 | lp_0946 | Glycosyltransferase, family 2. | Mucus-binding protein, LPXTG-motif cell wall anchor. | 0.589 |
| ica1 | sip1 | lp_1524 | lp_2862 | Glycosyltransferase, family 2. | Signal peptidase I; Belongs to the peptidase S26 family. | 0.438 |
| ica1 | sip2 | lp_1524 | lp_2863 | Glycosyltransferase, family 2. | Signal peptidase I; Belongs to the peptidase S26 family. | 0.637 |
| ica1 | sip3 | lp_1524 | lp_3675 | Glycosyltransferase, family 2. | Signal peptidase I; Belongs to the peptidase S26 family. | 0.617 |
| lp_0946 | ica1 | lp_0946 | lp_1524 | Mucus-binding protein, LPXTG-motif cell wall anchor. | Glycosyltransferase, family 2. | 0.589 |
| lp_0946 | sip1 | lp_0946 | lp_2862 | Mucus-binding protein, LPXTG-motif cell wall anchor. | Signal peptidase I; Belongs to the peptidase S26 family. | 0.516 |
| lp_0946 | sip2 | lp_0946 | lp_2863 | Mucus-binding protein, LPXTG-motif cell wall anchor. | Signal peptidase I; Belongs to the peptidase S26 family. | 0.622 |
| lp_0946 | sip3 | lp_0946 | lp_3675 | Mucus-binding protein, LPXTG-motif cell wall anchor. | Signal peptidase I; Belongs to the peptidase S26 family. | 0.622 |
| lspA | ffh | lp_1780 | lp_1635 | Signal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | Signal recognition particle protein Ffh; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.583 |
| lspA | secA | lp_1780 | lp_0739 | Signal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.592 |
| lspA | secE | lp_1780 | lp_0616 | Signal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | Preprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.488 |
| lspA | secG | lp_1780 | lp_0795 | Signal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.661 |