STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ropBTranscription regulator, TetR family. (303 aa)    
Predicted Functional Partners:
lp_2917
Transport protein, major facilitator superfamily (MFS).
 
   
 0.819
lp_1377
Hypothetical protein.
  
    0.631
gyrA
DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
      
 0.575
lp_2084
Transport protein, major facilitator superfamily (MFS).
 
   
 0.546
lp_2768
Transport protein, major facilitator superfamily (MFS).
 
     0.517
lp_2486
Mucus-binding protein, LPXTG-motif cell wall anchor.
  
    0.485
lp_2173
Cell surface protein, CscB family.
  
    0.474
lp_2975
Cell surface protein, CscC family.
  
    0.460
lp_3179
Hypothetical protein.
  
     0.455
lp_3064
Cell surface protein, CscC family.
  
    0.436
Your Current Organism:
Lactobacillus plantarum
NCBI taxonomy Id: 220668
Other names: L. plantarum WCFS1, Lactobacillus plantarum WCFS1, Lactobacillus plantarum str. WCFS1, Lactobacillus plantarum strain WCFS1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.