| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| apbE2 | def2 | lp_2936 | lp_2935 | Thiamin biosynthesis lipoprotein ApbE; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. | Formylmethionine deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins; Belongs to the polypeptide deformylase family. | 0.891 |
| apbE2 | hepA | lp_2936 | lp_1067 | Thiamin biosynthesis lipoprotein ApbE; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. | Heptaprenyl diphosphate synthase component I. | 0.684 |
| apbE2 | lp_0055 | lp_2936 | lp_0055 | Thiamin biosynthesis lipoprotein ApbE; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. | Fumarate reductase, flavoprotein subunit precursor. | 0.432 |
| apbE2 | lp_0952 | lp_2936 | lp_0952 | Thiamin biosynthesis lipoprotein ApbE; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. | Fumarate reductase, flavoprotein subunit precursor. | 0.416 |
| apbE2 | lp_1068 | lp_2936 | lp_1068 | Thiamin biosynthesis lipoprotein ApbE; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. | Extracellular protein, DUF1312 famliy. | 0.536 |
| apbE2 | lp_1546 | lp_2936 | lp_1546 | Thiamin biosynthesis lipoprotein ApbE; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. | 1,4-dihydroxy-2-naphthoate octaprenyltransferase, UbiA family. | 0.401 |
| apbE2 | lp_2732 | lp_2936 | lp_2732 | Thiamin biosynthesis lipoprotein ApbE; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. | NADPH-dependent FMN reductase family protein. | 0.405 |
| apbE2 | lp_3491 | lp_2936 | lp_3491 | Thiamin biosynthesis lipoprotein ApbE; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. | Fumarate reductase, flavoprotein subunit precursor. | 0.521 |
| apbE2 | urdA | lp_2936 | lp_1425 | Thiamin biosynthesis lipoprotein ApbE; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. | Fumarate reductase/succinate dehydrogenase,FAD-binding flavoprotein; Catalyzes the two-electron reduction of urocanate to dihydrourocanate (also named imidazole propionate or deamino- histidine). Dihydrourocanate is present at higher concentrations in subjects with type 2 diabetes, and directly impairs glucose tolerance and insulin signaling at the level of insulin receptor substrate (IRS) through activation of p38 gamma (MAPK12)-p62-mTORC1. Therefore, the UrdA enzyme from the gut bacteria L.plantarum strain WCFS1, may contribute to the pathogenesis of type 2 diabetes by producing the [...] | 0.590 |
| def2 | apbE2 | lp_2935 | lp_2936 | Formylmethionine deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins; Belongs to the polypeptide deformylase family. | Thiamin biosynthesis lipoprotein ApbE; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. | 0.891 |
| hepA | apbE2 | lp_1067 | lp_2936 | Heptaprenyl diphosphate synthase component I. | Thiamin biosynthesis lipoprotein ApbE; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. | 0.684 |
| hepA | lp_1068 | lp_1067 | lp_1068 | Heptaprenyl diphosphate synthase component I. | Extracellular protein, DUF1312 famliy. | 0.993 |
| hepA | lp_1546 | lp_1067 | lp_1546 | Heptaprenyl diphosphate synthase component I. | 1,4-dihydroxy-2-naphthoate octaprenyltransferase, UbiA family. | 0.775 |
| lp_0055 | apbE2 | lp_0055 | lp_2936 | Fumarate reductase, flavoprotein subunit precursor. | Thiamin biosynthesis lipoprotein ApbE; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. | 0.432 |
| lp_0055 | lp_2732 | lp_0055 | lp_2732 | Fumarate reductase, flavoprotein subunit precursor. | NADPH-dependent FMN reductase family protein. | 0.407 |
| lp_0055 | lp_3491 | lp_0055 | lp_3491 | Fumarate reductase, flavoprotein subunit precursor. | Fumarate reductase, flavoprotein subunit precursor. | 0.614 |
| lp_0055 | urdA | lp_0055 | lp_1425 | Fumarate reductase, flavoprotein subunit precursor. | Fumarate reductase/succinate dehydrogenase,FAD-binding flavoprotein; Catalyzes the two-electron reduction of urocanate to dihydrourocanate (also named imidazole propionate or deamino- histidine). Dihydrourocanate is present at higher concentrations in subjects with type 2 diabetes, and directly impairs glucose tolerance and insulin signaling at the level of insulin receptor substrate (IRS) through activation of p38 gamma (MAPK12)-p62-mTORC1. Therefore, the UrdA enzyme from the gut bacteria L.plantarum strain WCFS1, may contribute to the pathogenesis of type 2 diabetes by producing the [...] | 0.545 |
| lp_0952 | apbE2 | lp_0952 | lp_2936 | Fumarate reductase, flavoprotein subunit precursor. | Thiamin biosynthesis lipoprotein ApbE; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. | 0.416 |
| lp_0952 | lp_2732 | lp_0952 | lp_2732 | Fumarate reductase, flavoprotein subunit precursor. | NADPH-dependent FMN reductase family protein. | 0.409 |
| lp_0952 | lp_3491 | lp_0952 | lp_3491 | Fumarate reductase, flavoprotein subunit precursor. | Fumarate reductase, flavoprotein subunit precursor. | 0.758 |