Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
lp_3207PLP-dependent aminotransferase. (408 aa)    
Predicted Functional Partners:
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.914
gcsH1
Glycine cleavage system, H protein.
  
  
  0.912
glcD
Glycolate dehydrogenase, subunit GlcD,FAD-binding.
  
 
  0.908
glnA
Glutamate-ammonia ligase.
    
 0.905
pdhD
Pyruvate dehydrogenase complex, E3 component; dihydrolipoamide dehydrogenase.
     
  0.900
gcsH2
Glycine cleavage system, H protein.
     
  0.900
lp_3206
Transcription regulator, LysR family; Belongs to the LysR transcriptional regulatory family.
 
  
 0.669
gabT
4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
  
 0.447
lp_1905
Hypothetical protein; Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
   
    0.432
lp_3209
Cystine ABC transporter, substrate binding protein; Belongs to the bacterial solute-binding protein 3 family.
  
    0.422
Your Current Organism:
Lactobacillus plantarum
NCBI taxonomy Id: 220668
Other names: L. plantarum WCFS1, Lactobacillus plantarum WCFS1, Lactobacillus plantarum str. WCFS1, Lactobacillus plantarum strain WCFS1
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