Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
crtMDehydrosqualene synthase. (293 aa)    
Predicted Functional Partners:
crtN
Dehydrosqualene desaturase.
  
 0.999
lp_1602
Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
  
 0.899
uppS
Undecaprenyl pyrophosphate synthetase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
   
 
 0.840
gapB
Glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
  
 0.752
rpsA
30S ribosomal protein S1.
   
    0.667
lp_1386
Na+ driven multidrug efflux protein, MATE family.
   
  
 0.654
lp_0085
Multidrug extrusion protein (Na(+)/drug antiporter), MATE family of MDR efflux pumps.
   
  
 0.647
lp_2690
Short-chain dehydrogenase, atypical SDR family,subgroup 5.
 
 
 0.640
kat
Catalase; Belongs to the catalase family.
   
  
 0.593
mvaS
hydroxymethylglutaryl-CoA synthase.
   
 
 0.561
Your Current Organism:
Lactobacillus plantarum
NCBI taxonomy Id: 220668
Other names: L. plantarum WCFS1, Lactobacillus plantarum WCFS1, Lactobacillus plantarum str. WCFS1, Lactobacillus plantarum strain WCFS1
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