| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| crtM | crtN | lp_3263 | lp_3262 | Dehydrosqualene synthase. | Dehydrosqualene desaturase. | 0.999 |
| crtM | gapB | lp_3263 | lp_0789 | Dehydrosqualene synthase. | Glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.834 |
| crtM | hepA | lp_3263 | lp_1067 | Dehydrosqualene synthase. | Heptaprenyl diphosphate synthase component I. | 0.804 |
| crtM | hepB1 | lp_3263 | lp_1066 | Dehydrosqualene synthase. | Heptaprenyl diphosphate synthase component II; Belongs to the FPP/GGPP synthase family. | 0.898 |
| crtM | hepB2 | lp_3263 | lp_1134 | Dehydrosqualene synthase. | Heptaprenyl diphosphate synthase component II; Belongs to the FPP/GGPP synthase family. | 0.902 |
| crtM | lp_0085 | lp_3263 | lp_0085 | Dehydrosqualene synthase. | Multidrug extrusion protein (Na(+)/drug antiporter), MATE family of MDR efflux pumps. | 0.740 |
| crtM | lp_1386 | lp_3263 | lp_1386 | Dehydrosqualene synthase. | Na+ driven multidrug efflux protein, MATE family. | 0.733 |
| crtM | lp_1602 | lp_3263 | lp_1602 | Dehydrosqualene synthase. | Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 0.899 |
| crtM | rpsA | lp_3263 | lp_1882 | Dehydrosqualene synthase. | 30S ribosomal protein S1. | 0.714 |
| crtM | uppS | lp_3263 | lp_2051 | Dehydrosqualene synthase. | Undecaprenyl pyrophosphate synthetase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.835 |
| crtN | crtM | lp_3262 | lp_3263 | Dehydrosqualene desaturase. | Dehydrosqualene synthase. | 0.999 |
| gapB | crtM | lp_0789 | lp_3263 | Glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | Dehydrosqualene synthase. | 0.834 |
| gapB | lp_0085 | lp_0789 | lp_0085 | Glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | Multidrug extrusion protein (Na(+)/drug antiporter), MATE family of MDR efflux pumps. | 0.632 |
| gapB | lp_1386 | lp_0789 | lp_1386 | Glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | Na+ driven multidrug efflux protein, MATE family. | 0.632 |
| gapB | rpsA | lp_0789 | lp_1882 | Glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 30S ribosomal protein S1. | 0.722 |
| hepA | crtM | lp_1067 | lp_3263 | Heptaprenyl diphosphate synthase component I. | Dehydrosqualene synthase. | 0.804 |
| hepA | hepB1 | lp_1067 | lp_1066 | Heptaprenyl diphosphate synthase component I. | Heptaprenyl diphosphate synthase component II; Belongs to the FPP/GGPP synthase family. | 0.998 |
| hepA | hepB2 | lp_1067 | lp_1134 | Heptaprenyl diphosphate synthase component I. | Heptaprenyl diphosphate synthase component II; Belongs to the FPP/GGPP synthase family. | 0.960 |
| hepA | lp_1602 | lp_1067 | lp_1602 | Heptaprenyl diphosphate synthase component I. | Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 0.921 |
| hepA | uppS | lp_1067 | lp_2051 | Heptaprenyl diphosphate synthase component I. | Undecaprenyl pyrophosphate synthetase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.902 |