Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
czcD2Cation (cobalt-zinc-cadmium) efflux protein. (295 aa)    
Predicted Functional Partners:
pflE
Formate acetyltransferase activating enzyme.
   
  
 0.654
lp_3287
Transcription regulator, ArsR family.
  
  
 0.633
tkt3
Transketolase; Belongs to the transketolase family.
   
  
 0.598
ndk
Nucleoside-diphosphate kinase; Belongs to the NDK family.
  
  
 0.596
glpF3
Glycerol uptake facilitator protein; Transporter that facilitates the transmembrane diffusion of water, dihydroxyacetone, glycerol and H(2)O(2). Is not permeable to urea and D/L-lactic acid; Belongs to the MIP/aquaporin (TC 1.A.8) family.
   
  
 0.562
copR
Transcription regulator of CopAB ATPases.
  
  
 0.549
tkt1A
Transketolase, thiamine diphosphate binding domain.
      
 0.534
tkt2
Transketolase; Belongs to the transketolase family.
      
 0.533
infC
Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
      
 0.533
pps
Phosphoenolpyruvate synthase (pyruvate phosphate dikinase); Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
   
  
 0.533
Your Current Organism:
Lactobacillus plantarum
NCBI taxonomy Id: 220668
Other names: L. plantarum WCFS1, Lactobacillus plantarum WCFS1, Lactobacillus plantarum str. WCFS1, Lactobacillus plantarum strain WCFS1
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