STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
czcD2Cation (cobalt-zinc-cadmium) efflux protein. (295 aa)    
Predicted Functional Partners:
pflE
Formate acetyltransferase activating enzyme.
   
  
 0.715
lp_3287
Transcription regulator, ArsR family.
  
  
 0.598
ndk
Nucleoside-diphosphate kinase; Belongs to the NDK family.
  
  
 0.556
pps
Phosphoenolpyruvate synthase (pyruvate phosphate dikinase); Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
   
  
 0.550
infC
Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
      
 0.548
tkt3
Transketolase; Belongs to the transketolase family.
      
 0.547
glpF4
Glycerol uptake facilitator protein; Transporter that facilitates the transmembrane diffusion of water, dihydroxyacetone, glycerol, urea, H(2)O(2) and D/L-lactic acid. Is involved in the cellular racemization of lactate and lactate metabolism, but has likely a more general physiological role. The transported molecule is indeed lactic acid and not the lactate anion, in agreement with the assumption that, with very few exceptions, MIPs (major intrinsic proteins) only facilitate the transport of uncharged solutes.
   
  
 0.533
lp_3286
Hypothetical membrane protein, hemolysin III family.
 
  
 0.505
tkt1A
Transketolase, thiamine diphosphate binding domain.
      
 0.503
tkt2
Transketolase; Belongs to the transketolase family.
      
 0.503
Your Current Organism:
Lactobacillus plantarum
NCBI taxonomy Id: 220668
Other names: L. plantarum WCFS1, Lactobacillus plantarum WCFS1, Lactobacillus plantarum str. WCFS1, Lactobacillus plantarum strain WCFS1
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