STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pflAFormate C-acetyltransferase activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. (273 aa)    
Predicted Functional Partners:
pflB
Formate C-acetyltransferase.
  
 0.996
pflF
Formate C-acetyltransferase.
  
 0.953
pdhB
Pyruvate dehydrogenase complex, E1 component,beta subunit.
   
  
 0.777
adhE
Bifunctional protein: alcohol dehydrogenase; acetaldehyde dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
 
  
 0.772
ndk
Nucleoside-diphosphate kinase; Belongs to the NDK family.
   
  
 0.770
pdhC
Pyruvate dehydrogenase complex, E2 component; dihydrolipoamide S-acetyltransferase.
   
  
 0.761
pdhA
Pyruvate dehydrogenase complex, E1 component,alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
   
  
 0.743
pck
Phosphoenolpyruvate carboxykinase (ATP).
   
  
 0.733
lp_0240
Hypothetical protein.
   
    0.695
pts35C
PTS system, galactitol-specific EIIC component.
   
  
 0.640
Your Current Organism:
Lactobacillus plantarum
NCBI taxonomy Id: 220668
Other names: L. plantarum WCFS1, Lactobacillus plantarum WCFS1, Lactobacillus plantarum str. WCFS1, Lactobacillus plantarum strain WCFS1
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.