STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lp_3318Aldo/keto reductase family protein. (306 aa)    
Predicted Functional Partners:
pdhA
Pyruvate dehydrogenase complex, E1 component,alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
   
    0.702
gntR
Transcription regulator, GntR family.
  
    0.571
lp_0395
Hydrolase, HAD superfamily, Cof family.
  
    0.568
pflB
Formate C-acetyltransferase.
   
    0.562
lp_2219
6-phosphogluconolactonase.
   
    0.557
lp_1974
Transcription regulator of gluconeogenic genes; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
   
    0.554
ndk
Nucleoside-diphosphate kinase; Belongs to the NDK family.
   
    0.549
gabD
Succinate-semialdehyde dehydrogenase (NAD(P)+).
 
 
    0.549
pdhB
Pyruvate dehydrogenase complex, E1 component,beta subunit.
   
    0.529
lp_0240
Hypothetical protein.
   
    0.520
Your Current Organism:
Lactobacillus plantarum
NCBI taxonomy Id: 220668
Other names: L. plantarum WCFS1, Lactobacillus plantarum WCFS1, Lactobacillus plantarum str. WCFS1, Lactobacillus plantarum strain WCFS1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.